119067-41-3

Upstream product

• 118991-40-5 trans-4-acetyl-3-ethyl-1-(4-methoxyphenyl)azetidin-2-one 
• 100239-15-4 (E)-4-methoxy-N-((E)-2-methyl-3-phenylallylidene)aniline 
• 122673-11-4 1-(4-methoxyphenyl)-4-(α-methylstyryl)azetidin-2-one 
• 118991-37-0 3-ethyl-4-(α-methylstyryl)-1-(4-methoxyphenyl)azetidin-2-one 
• 124223-53-6 cis-1-p-anisyl-3-ethyl-4-carboxy-2-azetidinone 
• 546-67-8 lead(IV) tetraacetate 
• 104-94-9 4-methoxy-aniline 
• 124156-21-4 ethyl (4-methoxyphenylimino)acetate 
• 112113-99-2 3-Ethyl-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid 
• 124156-24-7 cis-1-p-anisyl-3-ethyl-4-carbethoxy-2-azetidinone 
• 124156-22-5 cis-1-(4-Methoxyphenyl)-3-vinyl-4-(methoxycarbonyl)-2-azetidinone 
• 124156-32-7 3-Eth-(E)-ylidene-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid ethyl ester 
• 124156-23-6 3-ethyl-4-methoxycarbonyl-1-(4-methoxyphenyl)azetidin-2-one 
• 124156-23-6 cis-3-Ethyl-4-(methoxycarbonyl)-1-(4-methoxyphenyl)azetidin-2-one 

Relevant academic research and scientific papers

β-Lactams via α,β-Unsaturated Acid Chlorides: Intermediates for Carbapenem Antibiotics

Stereocontrolled synthesis of α-vinyl β-lactams and their transformation to convenient intermediates for PS-5, PS-6, asparenomycin, and thienamycin are described.

The acid chloride-iminoester condensation: A direct approach to PS-5 and PS-6 intermediates and related compounds

The dehydrochlorination of alkanoyl chlorides with triethylamine in the presence of α-iminoesters produced 3-alkyl-4-alkoxycarbonyl β-lactams in excellent yields and high stereoselectivity.

The Reformatsky Type Reaction of Gilman and Speeter in the Preparation of Valuable β-Lactams in Carbapenem Synthesis: Scope and Synthetic Utility

The preparation of apppropriately substituted 3-alkyl β-lactams from the Reformatsky type reaction of Gilman and Speeter is described.Treatment of Schiff bases derived from α-methylcinnamaldehyde and amines with ethyl α-bromobutyrate or ethyl α-bromoisova