1190843-65-2

Upstream product

• 3282-30-2 pivaloyl chloride 
• 100-83-4 meta-hydroxybenzaldehyde 
• 134518-89-1 3-pivaloyloxybenzaldehyde 

Downstream Products

• 1190843-66-3 3-[(diethoxyphosphoryl)methyl]phenyl pivalate 
• 1190843-58-3 tert-butyl 4-(3-hydroxybenzylidene)-3-methylpiperidine-1-carboxylate 
• 1191250-53-9 tert-butyl 4-(3-[(2,2-dimethylpropanoyl)oxy]benzylidene)-3-methylpiperidine-1-carboxylate 
• 1191250-54-0 2-{3-[3-methylpiperidin-4-ylidenemethyl]phenoxy}-5-(trifluoromethyl)pyrimidine 
• 1191286-55-1 (3S,4E)-3-methyl-N-pyridin-3-yl-4-(3-{[5-(trifluoromethyl)pyrimidin-2-yl]oxy}benzylidene)piperidine-1-carboxamide 
• 1191286-54-0 (3R,4E)-3-methyl-N-pyridin-3-yl-4-(3-{[5-(trifluoromethyl)pyrimidin-2-yl]oxy}benzylidene)piperidine-1-carboxamide 

Relevant academic research and scientific papers

ETHER BENZYLIDENE PIPERIDINE 5-MEMBERED ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS

The present invention relates to compounds of the Formula (I), and pharmaceutically acceptable salts thereof, and their use in the treatment of FAAH-mediated diseases or condition.

ETHER BENZYLIDENE PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS

The present invention relates to compounds of Formula (I) wherein Ar is optionally substituted phenyl or 6-membered heteroaryl moiety, or a benzisoxazole, pyrrolopyridine, or benzotriazole group; or a pharmaceutically acceptable salt thereof; processes for the preparation of the compounds; intermediates used in the preparation of the compounds; compositions containing the compounds; and uses of the compounds in treating diseases or conditions associated with fatty acid amide hydrolase (FAAH) activity, including pain, urinary incontinence, overactive bladder, emesis, cognitive disorders, anxiety, depression, sleeping disorders, eating disorders, movement disorders, glaucoma, psoriasis, multiple sclerosis, cerebrovascular disorders, brain injury, gastrointestinal disorders, hypertension, or cardiovascular disease.

4- [3- (ARYLOXY) BENZYLIDENE] -3-METHYL PIPERIDINE 5-MEMBERED ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS

The present invention relates to compounds of Formula (I), wherein Ar is a 5-membered heteroaryl moiety and X, Y and Z are independently N or CH; or a pharmaceutically acceptable salt thereof; processes for the preparation of the compounds; intermediates used in the preparation of the compounds; compositions containing the compounds; and uses of the compounds in treating diseases or conditions associated with fatty acid amide hydrolase (FAAH) activity.

4- [3- (ARYLOXY) BENZYLIDENE] -3-METHYL PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS

The present invention relates to compounds of Formula (I), wherein Ar is optionally substituted phenyl or heteroaryl and X, Y and Z are independently N or CH; or a pharmaceutically acceptable salt thereof; processes for the preparation of the compounds; intermediates used in the preparation of the compounds; compositions containing the compounds; and uses of the compounds in treating diseases or conditions associated with fatty acid amide hydrolase (FAAH) activity.