1190850-84-0Relevant academic research and scientific papers
Ring-extended gramicidin S analogs Containing cis δ-sugar amino acid turn mimetics with varying ring size
Knijnenburg, Annemiek D.,Spalburg, Emile,Deneeling, Albert J.,Mars-Groenendijk, Roos H.,Noort, Daan,Grotenbreg, Gijsbert M.,Vandermarel, Gijs A.,Overkleeft, Herman S.,Overhand, Mark
, p. 2544 - 2561 (2013/03/13)
This article presents a series of ring-extended gramicidin S derivatives, 9-14, that have four ornithine residues as polar protonated side chains and one modified turn region containing a mono-functionalized cis-δ-oxetane, δ-furanoid, or δ-pyranoid sugar
Synthesis and biological evaluation of novel gramicidin s analogues
Tuin, Adriaan Willem,Palachanis, Dimitrios Konstantinos,Buizert, Annelies,Grotenbreg, Gijsbert Marnix,Spalburg, Emile,De Neeling, Albert J.,Mars-Groenendijk, Roos H.,Noort, Daan,Van Der Marel, Gijsbert A.,Overkleeft, Herman S.,Overhand, Mark
experimental part, p. 4231 - 4241 (2011/02/24)
The synthesis of three new analogues of the cyclic cationic antimicrobial peptide Gramicidin S is described. These derivatives contain a modified turn region in which the DPhe-Pro motif has been replaced by a constrained furanoid sugar amino ac
