1190866-02-4

Basic information

• Product Name: 6'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one
• Synonyms: 6'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one
• CAS NO: 1190866-02-4
• Molecular Formula: C13H14BrNO
• Molecular Weight: 280.16036
• Mol File: 1190866-02-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one(1190866-02-4)
• EPA Substance Registry System: 6'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one(1190866-02-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 1190866-02-4(Hazardous Substances Data)

Usage

Uses

6''-Bromo-1'',2''-dihydrospiro[cyclohexane-1,3''-indole]-2''-one is used in preparation of Dibenzo[b,f][1,4]thiazepinecarboxamides as hepatitis B core protein modulators.

Upstream product

• 111-24-0 1,5-dibromo-pentane 
• 99365-40-9 6-bromo-2,3-dihydro-1H-indole-2-one 
• 100487-82-9 4-bromo-2-nitro-benzoic acid methyl ester 
• 364-73-8 4-Bromo-1-fluoro-2-nitrobenzene 
• 6127-11-3 (4-bromo-2-nitrophenyl)acetic acid 
• 628-77-3 1,5-diiodopentane 

Relevant articles and documents

HEPATITIS B CORE PROTEIN MODULATORS

The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound of formula:

New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors

This invention is directed to new inhibitors of the p38 mitogen-activated protein kinase having the general formula (I) to processes for their preparation; to pharmaceutical compositions comprising them; and to their use in therapy.