1191-02-2Relevant articles and documents
A convenient triisobutylaluminium (TIBAL)-promoted Johnson-Claisen approach to γ,δ-unsaturated alcohols
Cosgrove, Kelly L.,McGeary, Ross P.
experimental part, p. 1749 - 1752 (2009/12/04)
Mixed ortho esters derived from allylic alcohols undergo methanol elimination in the presence of triisobutylaluminium (TIBAL) at room temperature to form mixed ketene acetals. TIBAL then promotes immediate Claisen rearrangement of these intermediates, and