119106-38-6 Usage
Description
(1S)-(-)-3-OXOCAMPHORSULFONYLIMINE 98+%, also known as (-)-Camosulfonimine, is a chiral sulfonylimine compound with a purity of 98% or higher. It is characterized by its camphor-like odor and is widely recognized for its high purity and chiral nature. (1S)-(-)-3-OXOCAMPHORSULFONYLIMINE 98+% serves as a versatile intermediate in the synthesis of various chiral compounds, including pharmaceuticals and agrochemicals. Its role as a key building block in the production of chiral sulfonylimine ligands is particularly noteworthy, as these ligands are extensively utilized in asymmetric catalysis and organic synthesis. (1S)-(-)-3-OXOCAMPHORSULFONYLIMINE 98+%'s attributes make it an invaluable tool for researchers and chemists in the development of new pharmaceuticals and other fine chemicals.
Uses
Used in Pharmaceutical Industry:
(1S)-(-)-3-OXOCAMPHORSULFONYLIMINE 98+% is used as a key intermediate for the synthesis of chiral compounds in the pharmaceutical industry. Its high purity and chiral nature are crucial for the development of new pharmaceuticals, ensuring the production of enantiomerically pure compounds that are essential for the effectiveness and safety of medications.
Used in Agrochemical Industry:
In the agrochemical industry, (1S)-(-)-3-OXOCAMPHORSULFONYLIMINE 98+% is utilized as a versatile intermediate for the synthesis of chiral agrochemicals. (1S)-(-)-3-OXOCAMPHORSULFONYLIMINE 98+%'s ability to produce enantiomerically pure products is vital for creating effective and environmentally friendly pesticides and other agricultural chemicals.
Used in Asymmetric Catalysis:
(1S)-(-)-3-OXOCAMPHORSULFONYLIMINE 98+% is used as a building block in the production of chiral sulfonylimine ligands, which are extensively applied in asymmetric catalysis. These ligands play a critical role in facilitating enantioselective reactions, leading to the production of chiral compounds with specific desired properties.
Used in Organic Synthesis:
(1S)-(-)-3-OXOCAMPHORSULFONYLIMINE 98+% is also used in organic synthesis as a valuable intermediate for creating a variety of chiral organic compounds. Its high purity and chiral nature make it an ideal candidate for synthesizing complex organic molecules with specific stereochemistry, which are important in various applications, including the development of new materials and the synthesis of natural products.
Check Digit Verification of cas no
The CAS Registry Mumber 119106-38-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,1,0 and 6 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 119106-38:
(8*1)+(7*1)+(6*9)+(5*1)+(4*0)+(3*6)+(2*3)+(1*8)=106
106 % 10 = 6
So 119106-38-6 is a valid CAS Registry Number.
119106-38-6Relevant articles and documents
Synthesis and characterization of novel spirooxazacamphorsultam derivatives
Wilke, Burkhardt I.,Goodenough, Angela K.,Bausch, Cory C.,Cline, Erika N.,Abrams, M. Leigh,Fayer, Effrat L.,Cermak, Diana M.
, p. 6871 - 6873 (2010)
Derivatives of camphorsultam which contain novel spirooxazolidine and spirooxazine structures have been prepared in high yield and purity. Though it was expected that the ketone moiety would undergo acetal formation, the imine instead underwent reaction and was proven by X-ray crystallography and 2D NMR techniques. The initial ketone-containing derivatives were then reduced to produce exo-hydroxy analogs that have potential as a new family of chiral auxiliaries.
Synthesis of alkynyl-substituted camphor derivatives and their use in the preparation of paclitaxel-related compounds
Carvalho, M. Fernanda N. N.,Herrmann, Rudolf,Wagner, Gabriele
, p. 1230 - 1238 (2017/07/03)
Compounds containing two alkyne groups in close vicinity at the rigid skeleton of camphorsulfonamide show unique reactivities when treated with electrophiles or catalytic amounts of platinum(II). The formed product structures depend not only on the reagents used but also on the substituents attached to the triple bonds. Cycloisomerisations with perfect atom economy lead to polycyclic heterocycles that resemble to some extent the AB ring system of paclitaxel. Herein, we present practical synthetic methods for the selective synthesis of precursor dialkynes bearing different substituents (alkyl, aryl) at the triple bonds, based on ketals or an imine as protecting groups. We show for isomeric dialkynes that the reaction cascade induced by Pt(II) includes ring annulation, sulphur reduction, and ring enlargement. One isomeric dialkyne additionally allows for the isolation of a pentacyclic compound lacking the ring enlargement step, which we have proposed as a potential intermediate in the catalytic cycle.
(+)-(3-Oxocamphorsulphonyl)oxaziridine as a Highly Stereoselective Reagent for the Oxidation of Sulphides to Chiral Sulphoxides
Glahsl, Gudrun,Herrmann, Rudolf
, p. 1753 - 1758 (2007/10/02)
The synthesis of the title oxaziridine and its application to the enantio- or diastereo-selective oxidation of sulphides to sulphoxides is described.Enantiomeric excesses up to 66percent are observed, showing the reagent to be superior to most other oxidizing systems.The exceedingly mild reaction conditions (aprotic, neutral) allow the preparation of several chiral α-sulphinyl aldehydes.The properties of these compounds are discussed.
