119125-40-5Relevant academic research and scientific papers
Synthesis of 5-(Acylethynyl)uracils and their Corresponding 2'-Deoxyribonucleosides through Palladium-catalysed Reactions
Kundu, Nitya G.,Dasgupta, Swapan K.
, p. 2657 - 2664 (2007/10/02)
Good yields of the title uracils were obtained by using the palladium-catalysed reaction between 5-iodo-2,4-dimethoxypyrimidine and substituted propargylic alcohols rather than the corresponding ketones.The same strategy works for coupling with the 5-iodo
AN EFFICIENT METHOD FOR THE IODINATION OF C5-POSITION OF DIALKOXY PYRIMIDINES AND URACIL BASES
Das, Biswajit,Kundu, Nitya G.
, p. 855 - 868 (2007/10/02)
N-Iodosuccinimide in trifluoroacetic acid and trifluoroacetic anhydride was found to be an excellent reagent for the conversion of 2,4-dialkoxy pyrimidines to 2,4-dialkoxy-5-iodopyrimidines.Iodination at C5-position of uracil and its derivatives was also accomplished with the above reagent.
