119138-37-3Relevant academic research and scientific papers
New Synthetic Route to N,N'-Diaminohydantoins from Hydrazido Pyridinium Salts
Florac, Claudie,Grel, Philippe Le,Baudy-Floc'h, Michele,Robert, Albert
, p. 1143 - 1146 (2007/10/02)
α-Bromoarylacetohydrazides were converted by pyridine into the corresponding arylacetylhydrazinopyridinium salts.Treated with triethylamine, these pyridinium salts afford 4-aryl-1,3-diaminohydantoins.The study of the mechanism of this unexpected reaction lead us to extend its scope to 4-arylhydantoins bearing two different substituted amino groups on nitrogens 1 and 3.
SYNTHESE EN UNE ETAPE D'α-ALCOXYHYDRAZIDES, DE DERIVES D'α-AMINOACIDES ET D'α-HYDROXYACIDES A PARTIR DES α-HALOGENOHYDRAZIDES. ETUDE DU MECANISME DE LA REACTION.
Legrel, P.,Baudy-Floc'h, M.,Robert, A.
, p. 4805 - 4814 (2007/10/02)
α-Halohydrazides react with nucleophiles under basic conditions to give α-functionalized hydrazides.We have shown that this reaction is not a direct nucleophilic substitution of the halogen but more likely proceeds through the formation of an aziridinone
