1192-29-6Relevant articles and documents
PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINE DERIVATIVE
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, (2011/11/06)
Optically active amine derivatives are produced by acting on imine derivatives with a culture of microorganisms having the ability to stereoselectively reduce the compounds, microbial cells, or processed products thereof, followed by collecting the generated optically active amine derivatives. Optically active amine derivatives obtained in the present invention are useful as materials for pharmaceutical agents. The present invention enables, for example, production of an optically active compound represented by formula (IV): (wherein R group represents an alkyl group having one to three carbon atoms; and n represents an integer of 1 to 4).
Intramolecular hydroamination of aminoalkynes with silver-phenanthroline catalysts
Carney, Jeffrey M.,Donoghue, Patrick J.,Wuest, William M.,Wiest, Olaf,Helquist, Paul
supporting information; experimental part, p. 3903 - 3906 (2009/07/09)
(Chemical Equation Presented) Intramolecular hydroamination of several aminoalkynes catalyzed by silver-phenanthroline complexes is reported. This catalyst system complements previous protocols by employing air- and moisture-stable complexes without compromising activity or reaction control. Some of the hydroamination products are subject to a useful aerobic oxidation. Silver-phenanthroline complexes have successfully demonstrated efficacy in the desymmetrization of a prochiral diyne.
Mechanistic investigation of intramolecular aminoalkene and aminoalkyne hydroamination/cyclization catalyzed by highly electrophilic, tetravalent constrained geometry 4d and 5f complexes. Evidence for an M-N σ-bonded insertive pathway
Stubbert, Bryan D.,Marks, Tobin J.
, p. 6149 - 6167 (2008/02/04)
A mechanistic study of intramolecular hydroamination/cyclization catalyzed by tetravalent organoactinide and organozirconium complexes is presented. A series of selectively substituted constrained geometry complexes, (CGC)M(NR 2)Cl (CGC = [Mes