1192006-26-0

Basic information

• Product Name: C₁₂H₁₈O₃
• Synonyms: C₁₂H₁₈O₃
• CAS NO: 1192006-26-0
• Molecular Weight: 210.273
• Mol File: 1192006-26-0.mol

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₈O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₈O₃(1192006-26-0)
• EPA Substance Registry System: C₁₂H₁₈O₃(1192006-26-0)

Safety Data

• Hazardous Substances Data: 1192006-26-0(Hazardous Substances Data)

Upstream product

• 86040-06-4 {[(2R)-pent-4-en-2-yloxy]methyl}benzene 
• 64584-92-5 (R)-pent-4-en-2-ol 
• 100-39-0 benzyl bromide 

Downstream Products

• 1192006-27-1 C₂₄H₄₆O₃Si₂ 
• 86040-07-5 (R)-3-benzyloxybutanal 

Relevant articles and documents

First Stereoselective Synthesis of the Cytotoxic Polyketide (4R)-1-(3,5-Dihydroxyphenyl)-4-hydroxypentan-2-one

The first stereoselective synthesis of the cytotoxic polyketide (4R)-1-(3,5-dihydroxyphenyl)-4-hydroxypentan-2-one (1) was achieved from readily available propylene oxide and 3,5-dimethoxybenzyl alcohol. The synthesis involves Jacobsen's hydrolytic kinetic resolution (HKR) and Grignard reaction as key steps.

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The oxidized abasic lesion 5′-(2-phosphoryl-1,4-dioxobutane) (DOB) is produced concomitantly with a single-strand break by a variety of DNA-damaging agents that abstract a hydrogen atom from the C5′-position. Independent generation of the DOB lesion in DN