1192159-92-4Relevant academic research and scientific papers
Platinum-catalyzed, one-pot tandem synthesis of indoles and isoquinolines via sequential rearrangement of amides and aminocyclization
Okamoto, Noriko,Takeda, Kei,Yanada, Reiko
experimental part, p. 7615 - 7625 (2011/02/25)
By using platinum(II) chloride as a Lewis acid catalyst, concise and efficient syntheses of indole carbamates, 1,2-dihydroisoquinoline carbamates, macrocyclic indole carbamates, indole ureas, and indole phosphoranes have been achieved via tandem Hofmann-t
Copper-catalyzed N-arylation/hydroamin(d)ation domino synthesis of indoles and its application to the preparation of a Chekl/KDR kinase inhibitor pharmacophore
Ackermann, Lutz,Barfuesser, Sebastian,Potukuchi, Harish K.
supporting information; experimental part, p. 1064 - 1072 (2010/03/03)
Inexpensive copper catalysts allow for efficient syntheses of N-aryl-, N-acyl-, or N-H-(aza)in-doles starting from ortho-alkynylbromoarenes. The broad scope of this domino N-arylation/hydro-amin(d)ation process is highlighted by the synthesis of highly fu
Concise one-pot tandem synthesis of indoles and isoquinolines from amides
Okamoto, Noriko,Miwa, Yoshihisa,Minami, Hideki,Takeda, Kei,Yanada, Reiko
supporting information; experimental part, p. 9693 - 9696 (2010/04/28)
Heterocyclic hot pot: Platinum[II]-catalyzed syntheses of indoles and isoquinolines from isocyanates, which are derived from a Hofmann-type rearrangement of amides using a hypervalent iodine reagent, are described. C2-symmetric macrocyclic bis[indole]s ca
