119225-49-9Relevant academic research and scientific papers
Synthesis of 3-Substituted Ethyl 4,4,4-Trichloro-2-cyanobutanoates via Michael Addition to Ethyl 4,4,4-Trichloro-2-cyano-2-butenoate
Gaudemar-Bardone, Francoise,Mladenova, Margarita,Gaudemar, Marcel
, p. 611 - 614 (1988)
The title compounds 2 and 3 are easily synthesized in good to excellent yields and high stereoselectivity by addition of various nucleophiles, such as organometallic reagents, alcohols, thiols, phosphorus compounds and aniline, to ethyl 4,4,4-trichloro-2-cyano-2-butenoate.
