119252-57-2Relevant academic research and scientific papers
Synthesis and biological activity of 4-methyl-3,5-dioxane derivatives as thromboxane A2 receptor antagonists
Marusawa, Hiroshi,Setoi, Hiroyuki,Kuroda, Akio,Sawada, Akihiko,Seki, Jiro,Motoyama, Yukio,Tanaka, Hirokazu
, p. 2635 - 2645 (2007/10/03)
The synthesis and biological activity of novel 4-methyl-3,5-dioxane analogues are described. All compounds were produced through modification of the substituent formally corresponding to the ω-octenol side chain of thromboxane A2 (TXA2/su
Oxygen-containing heterocyclic compound
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, (2008/06/13)
The invention relates to treatment of diseases caused by thromboxane A2 comprising administering a compound STR1 wherein R1 is hydrogen or lower alkyl, R2 is carboxy(lower)alkyl or protected carboxy(lower)alkyl and R3
Oxygen-containing hererocyclic compound, processes for their preparation and pharmaceutical compositions comprising them
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, (2008/06/13)
A compound of the formula : wherein, R1 is hydrogen or lower alkyl,R2 is carboxy(lower)alkyl or protected carboxy(lower)alkyl and, R3 is -CH2NH-R4, -CH=N-R4 or -CH2-R5, in which, R4 is acyl
