119259-99-3Relevant academic research and scientific papers
Preparation and acetylcholinesterase inhibitory activities of pyridine-based 1,3,4-oxadiazole derivatives
Chen, Yafang,Huang, Ling,Yang, Wude,Yu, Xiang,Zhou, Xingji
, p. 1163 - 1171 (2020/09/18)
Fourteen pyridine-based 1,3,4-oxadiazole derivatives were synthesized from pyridine-2-carboxaldehyde via iodine-mediated oxidative cyclisation with substituted hydrazide by using the impregnation method. Their structures were confirmed by melting point,
Mechanistic differences between in vitro assays for hydrazone-based small molecule inhibitors of anthrax lethal factor
Hanna, M. Leslie,Tarasow, Theodore M.,Perkins, Julie
, p. 50 - 58 (2008/09/18)
A systematically generated series of hydrazones were analyzed as potential inhibitors of anthrax lethal factor. The hydrazones were screened using one UV-based and two fluorescence-based in vitro assays. The study identified several inhibitors with IC50 values in the micromolar range, and importantly, significant differences in the types of inhibition were observed with the different assays.
Dynamic acylhydrazone metal ion complex libraries: A mixed-ligand approach to increased selectivity in extraction
Choudhary, Seema,Morrow, Janet R.
, p. 4096 - 4098 (2007/10/03)
The dynamic nature of metal-ligand interactions facilitates the formation of metal ion acylhydrazone complex libraries. From these libraries, metal ion complexes with two different types of ligands (1-14; R1≠R2) are shown to have sup
