119274-75-8

Basic information

• Product Name: N,N'-bis(N-(carbobenzyloxy)-L-valyl)-1,3-diaminopropane
• Synonyms: N,N'-bis(N-(carbobenzyloxy)-L-valyl)-1,3-diaminopropane
• CAS NO: 119274-75-8
• Molecular Weight: 540.66
• Mol File: 119274-75-8.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: N,N'-bis(N-(carbobenzyloxy)-L-valyl)-1,3-diaminopropane(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-bis(N-(carbobenzyloxy)-L-valyl)-1,3-diaminopropane(119274-75-8)
• EPA Substance Registry System: N,N'-bis(N-(carbobenzyloxy)-L-valyl)-1,3-diaminopropane(119274-75-8)

Safety Data

• Hazardous Substances Data: 119274-75-8(Hazardous Substances Data)

Upstream product

• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 109-76-2 Trimethylenediamine 
• 3496-11-5 2,5-dioxopyrrolidin-1-yl (2S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate 
• 119153-86-5 C₁₆H₂₁NO₆ 

Downstream Products

• 83852-29-3 (S,S)-N,N'-bis(phenylalanyl)-1,3-diaminopropane 

Relevant articles and documents

Molecular hydrogels from bolaform amino acid derivatives: A structure-properties study based on the thermodynamics of gel solubilization

Insight is provided into the aggregation thermodynamics associated to hydrogel formation by molecular gelators derived from L-valine and L-isoleucine. Solubility data from NMR measurements are used to extract thermodynamic parameters for the aggregation i

Diamine acylation with amino acid derivatives: An example of proximity effect in organic reactivity induced by supramolecular aggregation

Unexpected high yields of diamide 3 are obtained in the reaction of 1,3-propanediamine with an activated ester of l-valine (1) under adverse proportions of the reactants, namely in the presence of an excess of 1,3-propanediamine. It is observed using different conditions that the yield of difunctionalized compound is considerably higher than that expected from a statistical distribution of products. Proximity effects associated to supramolecular interactions explain the described reactivity.

Coordination of Cu2+ Ions to C 2 Symmetric pseudopeptides derived from valine

The acid-base and coordination properties of a family of pseudopeptidic ligands with C2 symmetry derived from valine (4a-e) have been studied using a variety of techniques as a model for metal coordination in peptides and proteins. The Cu2+ cation has been selected for coordination studies, although, for comparison, some results for Zn2+ are also presented. Good agreement has been obtained between the results obtained by potentiometric titrations, spectroscopic analysis, and mass spectrometry (ESI) studies. These results highlight the potential for the use of ESI MS for characterizing the nature of the complex species formed. Clearly, the Cu 2+ complexes are much more stable than the Zn2+ complexes. While the role of the aliphatic spacer seems to be very minor in the case of the Zn2+ complexes, revealing the ability of this cation to accommodate different coordination environments, this role is critical in the case of Cu2+. Different complexes with 1:1 or 2:2 Cu2+:L stoichiometries can be formed according to the length of the spacer and the basicity of the media. This is fully illustrated by the resolution of the X-ray structures of two different Cu2+ complexes corresponding to the ligands containing a spacer with two methylene groups (ligand 4a, complex 6a [Cu2(H-1L)2](ClO4)2 with a 2:2 stoichiometry) and a propylene spacer (4b, complex 5b [CuH-2L] CH3CH2OH with a 1:1 stoichiometry).