1193091-02-9Relevant academic research and scientific papers
δ-Di-carboxybutyl phosphoramidate of 2′-deoxycytidine-5′-monophosphate as substrate for DNA polymerization by HIV-1 reverse transcriptase
Zlatev, Ivan,Giraut, Anne,Morvan, Francois,Herdewijn, Piet,Vasseur, Jean-Jacques
, p. 7008 - 7014 (2009)
The replacement of the pyrophosphate moiety of 2′-deoxynucleoside triphosphates by non natural δ-dicarboxylic butyl amino acid allows incorporation of natural 2′-deoxycytidine into DNA using HIV-1 reverse transcriptase (RT) as enzyme. In contrast, the 3′-
