1193334-86-9

Basic information

• Product Name: 4-Bromo-1-cyclopropylpyridin-2(1H)-one
• Synonyms: 4-Bromo-1-cyclopropylpyridin-2(1H)-one
• CAS NO: 1193334-86-9
• Molecular Formula: C₈H₈BrNO
• Molecular Weight: 214.05922
• Mol File: 1193334-86-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 305.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.786±0.06 g/cm3(Predicted)
• PKA: -1.06±0.63(Predicted)
• CAS DataBase Reference: 4-Bromo-1-cyclopropylpyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-1-cyclopropylpyridin-2(1H)-one(1193334-86-9)
• EPA Substance Registry System: 4-Bromo-1-cyclopropylpyridin-2(1H)-one(1193334-86-9)

Safety Data

• Hazardous Substances Data: 1193334-86-9(Hazardous Substances Data)

Upstream product

• 36953-37-4 4-bromo-2(1H)-pyridinone 
• 411235-57-9 cyclopropylboronic acid 

Downstream Products

• 1254223-20-5 3-{(S)-1-[4-(1-cyclopropyl-2-oxo-1,2-dihydro-pyridin-4-yl)-2-methyl-phenyl]ethyl}-(S)-6-(2-hydroxy-2-methyl-propyl)-6-phenyl-[1,3]oxazinan-2-one 

Relevant articles and documents

HETEROCYCLIC COMPOUND AS CSF-1R INHIBITOR AND USE THEREOF

The present invention relates to a class of isoindolinone derivatives and use thereof in the preparation of a medicament for treating diseases associated with a novel colony stimulating factor 1 receptor (CSF-1R) inhibitor. In particular, the present invention relates to a compound of formula (I) and a pharmaceutically acceptable salt thereof or a stereoisomer thereof.

CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1

This invention relates to novel compounds of the Formula Ik, Im1, Im2, Im5, In1, In2, In5, Io1, Io2, Io5, Ip1, Ip3, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11β-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of cortisol in a cell or the inhibition of the conversion of cortisone to cortisol in a cell.