1193388-90-7Relevant articles and documents
Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes
Béliveau, Fran?ois,Tarkar, Aarti,Dion, Sébastien P.,Désilets, Antoine,Ghinet, Mariana Gabriela,Boudreault, Pierre-Luc,St-Georges, Catherine,Marsault, éric,Paone, Daniel,Collins, Jon,Macphee, Colin H.,Campobasso, Nino,Groy, Arthur,Cottom, Josh,Ouellette, Michael,Pope, Andrew J.,Leduc, Richard
, p. 1559 - 9,1572 (2019)
Iron overload disorders are characterized by the body's inability to regulate iron absorption and its storage which can lead to organ failures. Accumulated evidence has revealed that hepcidin, the master regulator of iron homeostasis, is negatively modula