1194-66-7

Basic information

• Product Name: 2,6-DICHLORONITROSOBENZENE
• Synonyms: 2,6-DICHLORONITROSOBENZENE;1,3-Dichloro-2-nitrosobenzene;2,6-DICHLORONITROSOBENZENE 98%
• CAS NO: 1194-66-7
• Molecular Formula: C₆H₃Cl₂NO
• Molecular Weight: 176
• Mol File: 1194-66-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 170-171°C
• Boiling Point: 271.9 °C at 760 mmHg
• Flash Point: 120.5 °C
• Appearance: /
• Density: 1.45 g/cm³
• Vapor Pressure: 0.0105mmHg at 25°C
• Refractive Index: 1.588
• CAS DataBase Reference: 2,6-DICHLORONITROSOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DICHLORONITROSOBENZENE(1194-66-7)
• EPA Substance Registry System: 2,6-DICHLORONITROSOBENZENE(1194-66-7)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 1194-66-7(Hazardous Substances Data)

Usage

General Description

2,6-Dichloronitrosobenzene is a synthetic, organic compound with the formula C6H3Cl2NO. This chemical, categorized as a nitroso compound and a dichlorobenzene, is predominantly used in research and industrial settings. Primarily, it serves as a building block in the synthesis of other complex organic compounds. As with many chemicals, it demands careful handling due to its potential toxicity and environmental harm. Despite this, thorough and appropriate safety methods can mitigating these risks, making 2,6-Dichloronitrosobenzene a valuable asset in the sphere of chemical synthesis.

InChI:InChI=1/C6H3Cl2NO/c7-4-2-1-3-5(8)6(4)9-10/h1-3H

Upstream product

• 6579-27-7 2,6-Dichloro-N-hydroxybenzenecarboximidoyl chloride 
• 3032-92-6 4-cyanophenylacetylene 
• 100045-99-6 2,6-dichloronitrosobenzene dimer 
• 608-31-1 2,6-Dichloroaniline 

Downstream Products

• 7116-16-7 4-chloro-2,1,3-benzoxadiazole 
• 32847-25-9 N-(2,6-dichlorophenyl)hydroxylamine 
• 138188-77-9 (Z)-3-[1-(2,6-Dichloro-phenyl)-aziridin-2-yl]-propenal 
• 138188-76-8 (1S,2S,4R,6S)-7-(2,6-Dichloro-phenyl)-3-oxa-7-aza-tricyclo[4.1.0.0^2,4]heptane 
• 863975-19-3 3-(2,6-dichlorophenyl)-5-(4-cyanophenyl)isoxazole 
• 81432-12-4 (S)-1-(7-Nitro-benzo[1,2,5]oxadiazol-4-yl)-pyrrolidine-2-carboxylic acid 
• 174844-42-9 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose 
• 927664-20-8 C₁₅H₁₄N₄O₄ 
• 1060798-84-6 4-(dimethylamino)-2,6-dichloronitrosobenzene 
• 916853-01-5 μ2-(η2-N,O-2,6-dichloronitrosobenzene)bis[μ-bromotricarbonylrhenium(I)] 
• 18378-29-5 4-methylamino-7-nitro-2,1,3-benzoxadiazole 
• 1455-87-4 N,N-dimethyl-7-nitrobenzo[c][1,2,5]oxadiazol-4-amine 
• 10199-91-4 4-amino-7-nitro-2,1,3-benzoxadiazole 
• 10199-89-0 NBD chloride 

Relevant articles and documents

Improved synthesis of 4-amino-7-nitrobenz-2,1,3-oxadiazoles using NBD fluoride (NBD-F)

The 7-nitrobenz-2,1,3-oxadiazole (NBD) unit is a highly useful fluorescent tag with wide application in biology. Installation of the NBD group typically proceeds via the SNAr reaction between an amine and an NBD halide. Herein, we demonstrate that NBD-F 1 results in significantly higher yields than NBD-Cl 2, and that triethylamine in dimethylformamide at 23 °C overnight is a broadly applicable set of conditions for this reaction. In particular, the highly useful fluorescent carbohydrate 2-NBD-glucosamine (2-NBDG, 3) can now be prepared in 75% yield with NBD-F as compared to 12% with NBD-Cl.

PRESSURE EFFECT ON DIMERIZATION EQUILIBRIA OF A SERIES OF SUBSTITUTED NITROSOBENZENES IN SOLUTION.

The effect of pressure was studied on the dimerization reactions of six di- and tri-substituted nitrosobenzenes in carbon tetrachloride at 25 degree C. The obtained configurational volume changes for the prototype one bond formation reactions are in the range of minus 17 to minus 21 cm**3 mol** minus **1 at 6. 13 MPa. The volume changes were interpreted in terms of the perturbation theory of liquid; they were dominated by the volume change in the reference system composed of hard spheres. Small differences between the observed and theoretical reference volume changes were ascribed to the perturbation due to electrostatic interactions between the solute and solvent; the perturbation volume changes were estimated by the Kirkwood theory of dipolar solvation.