1194-78-1

Usage

Uses

Used in Pharmaceutical Industry:
2,4,5-Triamino-6-chloropyrimidine is used as a building block for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Agrochemical Industry:
In the agrochemical industry, 2,4,5-Triamino-6-chloropyrimidine is used as a precursor for the synthesis of various agrochemicals, such as herbicides, pesticides, and fungicides. Its versatile chemical properties enable the creation of effective compounds for crop protection and enhancement of agricultural productivity.
Used in Research and Development:
2,4,5-Triamino-6-chloropyrimidine serves as an important research compound in the field of organic chemistry. It is utilized in the study of pyrimidine-based compounds and their potential applications in various chemical and biological processes. Researchers use 2,4,5-Triamino-6-chloropyrimidine to explore new synthetic routes, understand its reactivity, and investigate its potential interactions with other molecules.
Used in Material Science:
2,4,5-Triamino-6-chloropyrimidine can be employed in the development of novel materials with specific properties, such as high thermal stability, chemical resistance, or unique optical characteristics. Its incorporation into polymers or other materials can lead to the creation of advanced materials for various applications, including electronics, coatings, and sensors.

InChI:InChI=1/C4H6ClN5/c5-2-1(6)3(7)10-4(8)9-2/h6H2,(H4,7,8,9,10)

Upstream product

• 5822-69-5 6-chloro-5-<(4-chlorophenyl)azo>-2,4-pyrimidinediamine 
• 105-56-6 ethyl 2-cyanoacetate 
• 55583-59-0 2,5-diamino-4,6-dichloropyrimidine 

Downstream Products

• 88780-84-1 7-chloro-1H-[1,2,3]triazolo[4,5-d]pyrimidine-5-amine 
• 10310-21-1 2-amino-6-chloropurine 

Relevant academic research and scientific papers

2-amino-6-chloropurine as well as synthesis method, intermediate and application thereof

The invention belongs to the technical field of medicines and in particular relates to 2-amino-6-chloropurine as well as a synthesis method, an intermediate and application thereof. The synthesis method of the 2-amino-6-chloropurine comprises the following steps: performing a primary reaction, namely mixing ethyl cyanoacetate, chloroformamidine hydrochloride, liquid ammonia and sodium to implementa reaction so as to generate an intermediate; performing a secondary reaction, namely mixing the intermediate with formic acid to implement a reaction; adding a sodium hydroxide solution into the product of the secondary reaction till alkali; and performing filtering and drying, so as to obtain 2-amino-6-chloropurine. Raw materials are low in price and easy to obtain, reaction steps are small, the reaction time is short, a large amount of wastewater is not generated, and industrial production can be facilitated.

COMPOUNDS FOR TREATING CYSTIC FIBROSIS

The present invention relates to compounds of Formula (I) or pharmaceutically acceptable enantiomers, salts, solvates or prodrugs thereof. The invention further relates to the use of the compounds of Formula (I) for the treatment of cystic fibrosis. The invention also relates to a process for manufacturing compounds of Formula (I).

COMPOUNDS FOR IMPROVING MRNA SPLICING

Provided herein are compounds useful for improving mRNA splicing in a cell. Exemplary compounds provided herein are useful for improving mRNA splicing in genes comprising at least one exon ending in the nucleotide sequence CAA. Methods for preparing the compounds and methods of treating diseases of the central nervous system are also provided.

Bis (hydroxymethyl) cyclobutyl purines

Antiviral activity is exhibited by compounds having the formula STR1 and its pharmaceutically acceptable salts wherein R1 is STR2 wherein R2 is hydrogen, methyl, fluoro, chloro, bromo, iodo, hydroxy or amino; or trifluoromethyl; Rsu

Bis (hydroxymethyl) cyclobutyl triazolopyrimidines

Antiviral activity is exhibited by compounds having the formula STR1 and its pharmaceutically acceptable salts wherein R1 is STR2 R6 is hydrogen, alkyl, substituted alkyl, or aryl; and R7 and R8 are independentl