119433-00-0Relevant academic research and scientific papers
NEW STRATEGY IN THE STEREOCONTROLLED SYNTHESIS OF THE SPIRO KETAL SUBUNIT OF MILBEMYCINS
Bac, Nguyen Van,Langlois, Yves
, p. 2819 - 2822 (1988)
A double Baeyer-Villiger oxidation of bicyclo heptane-2,5-dione and a stereocontrolled alkylation of the dianion derived from 4-pentyn-2-ol are the salient features of a new strategy in the stereocontrolled synthesis of the spiroketal moiety of milbemycins.
Palladium- and copper-catalyzed 1,4-additions of organozinc compounds to conjugated aldehydes
Marshall, James A.,Herold, Martin,Eidam, Hilary S.,Eidam, Patrick
, p. 5505 - 5508 (2007/10/03)
Conjugated aldehydes undergo smooth Pd(OAc)2·PPh 3- or Me2CuCNLi2-catalyzed 1,4-addition of dialkylzinc reagents.
