1194550-61-2 Usage
Uses
Used in Pharmaceutical Synthesis:
2(1H)-Isoquinolinecarboxylic acid, 5,7-dichloro-3,4-dihydro-6-[[[(1S)-1-[[3-(methylsulfonyl)phenyl]methyl]-2-oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]-, 1,1-dimethylethyl ester is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique molecular structure allows it to be a versatile building block for the development of new drugs with potential therapeutic applications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2(1H)-Isoquinolinecarboxylic acid, 5,7-dichloro-3,4-dihydro-6-[[[(1S)-1-[[3-(methylsulfonyl)phenyl]methyl]-2-oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]-, 1,1-dimethylethyl ester is employed as a research tool to explore the structure-activity relationships of drug candidates. Its presence in various chemical libraries aids researchers in identifying potential lead compounds for the treatment of different diseases.
Used in Drug Discovery:
2(1H)-Isoquinolinecarboxylic acid, 5,7-dichloro-3,4-dihydro-6-[[[(1S)-1-[[3-(methylsulfonyl)phenyl]methyl]-2-oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]-, 1,1-dimethylethyl ester is used in drug discovery processes to screen for compounds with specific biological activities. Its unique structural features make it a candidate for high-throughput screening assays, which can lead to the identification of novel therapeutic agents.
Used in Biochemical Assays:
2(1H)-Isoquinolinecarboxylic acid, 5,7-dichloro-3,4-dihydro-6-[[[(1S)-1-[[3-(methylsulfonyl)phenyl]methyl]-2-oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]-, 1,1-dimethylethyl ester can be employed in biochemical assays to study enzyme inhibition, receptor binding, or other biological interactions. Its presence in assays can help researchers understand the mechanisms of action of potential drugs and their interactions with biological targets.
Check Digit Verification of cas no
The CAS Registry Mumber 1194550-61-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,4,5,5 and 0 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1194550-61:
(9*1)+(8*1)+(7*9)+(6*4)+(5*5)+(4*5)+(3*0)+(2*6)+(1*1)=162
162 % 10 = 2
So 1194550-61-2 is a valid CAS Registry Number.
1194550-61-2Relevant academic research and scientific papers
PROCESS FOR PREPARATION OF LIFITEGRAST
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Paragraph 0207, (2019/04/11)
The present invention relates to a process for the preparation of lifitegrast, a compound of formula I, the process comprising deprotecting a compound of formula III using a Lewis acid. The present invention also relates to lifitegrast organic amine salt, a compound of formula II, process for its preparation and conversion thereof to lifitegrast.
A PROCESS TO OBTAIN A TETRAHYDROISOQUINOLINE DERIVATIVE
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, (2019/06/09)
The present invention relates to a process for preparing lifitegrast or a salt thereof, wherein the process comprises hydrogenation of compound II in a mixture comprising at least one solvent selected from the group consisting of acetonitrile, a ketone solvent, an ester solvent and a mixture thereof, preferably acetonitrile.
LFA-1 INHIBITOR AND POLYMORPH THEREOF
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Paragraph 00147; 00148; 00150; 00151, (2014/02/16)
Methods of preparation and purification of a compound, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA -1 mediated diseases are also disclosed.
