119540-34-0Relevant articles and documents
SAR studies of 1,5-diarylpyrazole-based CCK1 receptor antagonists
Gomez, Laurent,Hack, Michael D.,McClure, Kelly,Sehon, Clark,Huang, Liming,Morton, Magda,Li, Lina,Barrett, Terrance D.,Shankley, Nigel,Breitenbucher, J. Guy
, p. 6493 - 6498 (2008/04/02)
A high throughput screening campaign revealed compound 1 as a potent antagonist of the human CCK1 receptor. Here, we report the syntheses and SAR studies of 1,5-diarylpyrazole analogs with various structural modifications of the alkane side cha
Alpha,beta-unsaturated esters and acids by stereoselective dehydration
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Page/Page column 58, (2010/02/15)
There are provided by the present invention certain pyrazole based CCK-1 receptor modulators which have the general formula: wherein Ar is an aromatic or heteroaromatic group, X is a hydrocarbon linker, Y is a bond or hydrocarbon linker and R1, R2, R3, R4 and R5 are certain organic substituents, methods for making the same, and stereoselective dehydration methods for generally making α,β-unsaturated esters, acids and their derivatives.
CCK-1 RECEPTOR MODULATORS
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Page 138, (2008/06/13)
There are provided by the present invention certain pyrazole based CCK-1 receptor modulators.