119584-78-0 Usage
General Description
2,4-DIAMINO-7-FLUOROQUINAZOLINE is a chemical compound with the molecular formula C8H6N6F. It is a fluorinated quinazoline derivative that is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. 2,4-DIAMINO-7-FLUOROQUINAZOLINE is of interest in medicinal chemistry due to its potential as a scaffold for the development of new drugs, particularly in the field of anti-cancer and anti-inflammatory agents. Its unique structure and reactivity make it a valuable tool for the discovery and development of novel therapeutic compounds. Additionally, 2,4-DIAMINO-7-FLUOROQUINAZOLINE has also been studied for its potential applications in materials science, such as in the development of organic semiconductor materials. Overall, this compound is a versatile and important building block in both pharmaceutical and materials research.
Check Digit Verification of cas no
The CAS Registry Mumber 119584-78-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,5,8 and 4 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 119584-78:
(8*1)+(7*1)+(6*9)+(5*5)+(4*8)+(3*4)+(2*7)+(1*8)=160
160 % 10 = 0
So 119584-78-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H7FN4/c9-4-1-2-5-6(3-4)12-8(11)13-7(5)10/h1-3H,(H4,10,11,12,13)
119584-78-0Relevant articles and documents
SNAr reaction in aqueous medium in the presence of mixed organic and inorganic bases
Shelke, Nilesh B.,Ghorpade, Ramrao,Pratap, Ajay,Tak, Vijay,Acharya
, p. 31226 - 31230 (2015/04/22)
N-Arylation of amines with fluorobenzonitriles in aqueous medium is described. A mixture of N,N-diisopropylethyl amine and Na2CO3 (1:1) is found to achieve maximum conversion by refluxing for 3 hours in water. The product can be easily isolated by solvent extraction.
Isoquinoline, Quinazoline and Phthalazine Derivatives
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Page/Page column 46, (2008/06/13)
Disclosed are compounds and pharmaceutically acceptable salts of Formula I wherein R0, R5, R6, R7, n, Q1-Q5, Y, and X1-X3 are as defined herein. Compounds of Formula I are useful in the treatment of diseases and/or conditions related to cell proliferation, such as cancer, inflammation, arthritis, angiogenesis, or the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds.
