1196-40-3

Basic information

• Product Name: Octahydro-4-methyl-2H-quinolizine
• Synonyms: 4-Lupinane;Octahydro-4-methyl-2H-quinolizine
• CAS NO: 1196-40-3
• Molecular Formula: C10H19 N
• Molecular Weight: 153.26
• Mol File: 1196-40-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Octahydro-4-methyl-2H-quinolizine(CAS DataBase Reference)
• NIST Chemistry Reference: Octahydro-4-methyl-2H-quinolizine(1196-40-3)
• EPA Substance Registry System: Octahydro-4-methyl-2H-quinolizine(1196-40-3)

Safety Data

• Hazardous Substances Data: 1196-40-3(Hazardous Substances Data)

Upstream product

• 100370-10-3 ethyl 4-(6-methylpyridin-2-yl)butanoate 
• 934-78-1 2-(6-methylpyridin-2-yl)-ethanol 
• 1122-70-9 2-methyl-6-vinylpyridine 
• 100-69-6 2-vinylpyridine 
• 95448-64-9 cis-Methyl 2-(3-Cyanopropyl)-6-methylpiperidine-1-carboxylate 
• 95448-68-3 cis-2-(3-Ethoxycarbonylpropyl)-6-methylpiperidine 
• 95448-61-6 N-methoxycarbonyl-6-aminohept-1-ene 
• 1462-92-6 6-methyl-2,3,4,5-tetrahydro-pyridine 
• 5504-64-3 cis-4-methylperhydroquinolizin-6-one 
• 5520-37-6 4-Methyl-chinolizinylium-bromid 
• 90874-87-6 1-(2-pyridyl)pentan-4-one 
• 90978-08-8 6-methyl-octahydro-quinolizin-4-one 
• 57606-77-6 6-hepten-2-one oxime 
• 95448-64-9 trans-Methyl 2-(3-Cyanopropyl)-6-methylpiperidine-1-carboxylate 

Downstream Products

• 106480-00-6 (+/-)-4t,5t-dimethyl-(9ar)-octahydro-quinolizinium; picrate 
• 106480-00-6 (+/-)-4c,5ξ-dimethyl-(9ar)-octahydro-quinolizinium; picrate 

Relevant articles and documents

Hydroformylation of alkenylamines. Concise approaches toward piperidines, quinolizidines, and related alkaloids

Linear hydroformylation of N-protected allyl- or homoallylamines (cyclohydrocarbonylation: CHC), followed by a reductive amination constitute the two key steps toward convenient routes to aza-heterocycles.

Synthesis of trans-2,6-Dialkylpiperidines by Intramolecular Amidomercuriation and by 1,3-Cycloaddition of Alkenes to 2-Methyl-2,3,4,5-tetrahydropyridine Oxide

Intramolecular amidomercuriation of methyl N-hept-6-en-2-ylcarbamate and reaction of the resulting organomercurial with sodium borohydride in the presence of acrylonitrile or dec-1-en-3-one has been used to prepare trans-2,6-dialkylpiperidines.A more stereoselective route lies in the cycloaddition of alkenes to 2-alkyl-2,3,4,5-tetrahydropyridine oxides followed by reductive cleavage of the resulting perhydroisoxazolopyridine.Both procedures are illustrated by synthesis of the fire ant-venom alkaloid, solenopsin A.