1196-72-1

Basic information

• Product Name: 2-Ureidophenol
• Synonyms: 1-(2-Hydroxyphenyl)urea;2-Ureidophenol;N-(2-Hydroxyphenyl)urea
• CAS NO: 1196-72-1
• Molecular Formula: C₇H₈N₂O₂
• Molecular Weight: 152.1506
• Mol File: 1196-72-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 279.2°Cat760mmHg
• Flash Point: 122.7°C
• Appearance: /
• Density: 1.407g/cm³
• Vapor Pressure: 0.0024mmHg at 25°C
• Refractive Index: 1.689
• CAS DataBase Reference: 2-Ureidophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Ureidophenol(1196-72-1)
• EPA Substance Registry System: 2-Ureidophenol(1196-72-1)

Safety Data

• Hazardous Substances Data: 1196-72-1(Hazardous Substances Data)

Usage

General Description

2-Ureidophenol, also known as 2-ureido-phenol or 2-hydroxybenzourea, is a chemical compound with the molecular formula C7H7N3O2. It is a white to off-white powder with a faint odor and is soluble in water. 2-Ureidophenol has various uses, including as an intermediate in the production of pharmaceuticals and dyes, as well as in organic synthesis. It is also used in the manufacturing of rubber and plastic compounds. Additionally, 2-ureidophenol has been studies for its potential applications in the field of medicine, specifically in the development of antitumor agents and as a potential biomarker for certain diseases. Overall, 2-ureidophenol is a versatile chemical compound with a wide range of industrial and potential medical applications.

InChI:InChI=1/C7H8N2O2/c8-7(11)9-5-3-1-2-4-6(5)10/h1-4,10H,(H3,8,9,11)

Upstream product

• 54539-61-6 2-hydroxybenzoyl azide 
• 69-72-7 salicylic acid 
• 95-55-6 2-amino-phenol 
• 43112-69-2 o-(trimethylsilyloxy)phenyl isocyanate 
• 75226-86-7 (2-Trimethylsilanyloxy-phenyl)-urea 
• 51-19-4 2-aminophenol hydrochloride 
• 57-13-6 urea 
• 590-28-3 potassium cyanate 
• 151-50-8 potassium cyanide 

Downstream Products

• 1351860-85-9 C₁₄H₁₂N₂O₃ 
• 857264-61-0 N-{2-[(2R)-oxiran-2-ylmethoxy]phenyl}urea 
• 27087-39-4 2-oxo-benzooxazole-3-carboxylic acid 4-nitro-phenyl ester 
• 59-49-4 2-Benzoxazolinone 
• 20844-72-8 2-oxo-benzooxazole-3-carboxylic acid amide 
• 140678-01-9 phenyl 2-ureidophenylcarbonate 
• 140678-02-0 p-nitrophenyl 2-ureidophenylcarbonate 
• 140678-00-8 ethyl 2-ureidophenylcarbonate 
• 55302-65-3 C₁₇H₂₀N₄O₄ 
• 51073-19-9 N-[2-(2-oxiranylmethoxy)phenyl]urea 
• 24963-28-8 3-acetylbenzo[d]oxazol-2(3H)-one 

Relevant articles and documents

Direct conversion of carboxylic acids to various nitrogen-containing compounds in the one-pot exploiting curtius rearrangement

Herein we report, a single-pot multistep conversion of inactivated carboxylic acids to various N-containing compounds using a common synthetic methodology. The developed methodology rendered the use of carboxylic acids as a direct surrogate of primary amines, for the synthesis of primary ureas, secondary/tertiary ureas, O/S-carbamates, benzoyl ureas, amides, and N-formyls, exploiting the Curtius reaction. This approach has a potential to provide a diversified library of N-containing compounds, starting from a single carboxylic acid, based on the selection of the nucleophile.

Coordination compounds of Schiff base containing urea moiety

A MeOH solution of salicylaldehyde and o-hydroxyphenylurea in equimolar ratio reacts and forms the Schiff base, LH3 (1). The latter reacts with CuII, ZnII, CdII, MnII, CoII, NiII, FeIII, MoO2II, UO2II and Zr(OH)

Novel compounds

The invention provides compounds of general formula (I) wherein Q, R, R2, R4, R5, R6, R7 and R8 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.