1196156-84-9

Basic information

• Product Name: 2-AMINO-6-METHOXY-NICOTINIC ACID
• Synonyms: 2-AMINO-6-METHOXY-NICOTINIC ACID;2-Amino-6-methoxynicotinic acid hydrochloride
• CAS NO: 1196156-84-9
• Molecular Formula: C₇H₈N₂O₃
• Molecular Weight: 168.15002
• Mol File: 1196156-84-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-AMINO-6-METHOXY-NICOTINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-6-METHOXY-NICOTINIC ACID(1196156-84-9)
• EPA Substance Registry System: 2-AMINO-6-METHOXY-NICOTINIC ACID(1196156-84-9)

Safety Data

• Hazardous Substances Data: 1196156-84-9(Hazardous Substances Data)

Usage

General Description

2-AMINO-6-METHOXY-NICOTINIC ACID is a chemical compound with the molecular formula C7H8N2O3. It is a derivative of nicotinic acid, also known as vitamin B3, and contains an amino group and a methoxy group. 2-AMINO-6-METHOXY-NICOTINIC ACID has shown potential therapeutic properties, including anti-inflammatory and antiviral activities. It is currently being studied for its potential use in the treatment of various diseases, including cancer and viral infections. Additionally, 2-AMINO-6-METHOXY-NICOTINIC ACID has also been investigated for its potential use as a building block in the synthesis of biologically active compounds. Overall, this chemical compound has garnered interest for its potential pharmaceutical and medicinal applications.

Upstream product

• 124-41-4 sodium methylate 
• 58584-92-2 2-amino-6-chloronicotinic acid 
• 67-56-1 methanol 
• 38496-18-3 2,6-dichloropyridine-3-carboxylic acid 
• 503000-87-1 2-chloro-6-methoxypyridine-3-carboxylic acid 
• 95652-77-0 methyl 2-chloro-6-methoxypyridine-3-carboxylate 
• 1298123-87-1 methyl 6-methoxy-2-((4-methoxybenzyl)amino)nicotinate 
• 1227048-93-2 methyl 2-amino-6-methoxynicotinate 

Downstream Products

• 1005490-30-1 C₁₄H₁₂N₄O₂ 

Relevant articles and documents

Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5

The availability of a chemical probe to study the role of a specific domain of a protein in a concentration- and time-dependent manner is of high value. Herein, we report the identification of a highly potent and selective ERK5 inhibitor BAY-885 by high-throughput screening and subsequent structure-based optimization. ERK5 is a key integrator of cellular signal transduction, and it has been shown to play a role in various cellular processes such as proliferation, differentiation, apoptosis, and cell survival. We could demonstrate that inhibition of ERK5 kinase and transcriptional activity with a small molecule did not translate into antiproliferative activity in different relevant cell models, which is in contrast to the results obtained by RNAi technology.

IDENTIFICATION AND USE OF ERK5 INHIBITORS

The present invention covers heterocyclic compounds of general formula (I) in which T, U, Y, Z, R1 and R3 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of cancer disorders, as a sole agent or in combination with other active ingredients.