1196157-14-8

Basic information

• Product Name: 4-broMo-5-Methylpicolinaldehyde
• Synonyms: 4-broMo-5-Methylpicolinaldehyde;4-bromo-5-methylpyridine-2-carbaldehyde
• CAS NO: 1196157-14-8
• Molecular Formula: C7H6BrNO
• Molecular Weight: 200.03264
• Mol File: 1196157-14-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 268.0±35.0 °C(Predicted)
• Appearance: /
• Density: 1.577±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.07±0.10(Predicted)
• CAS DataBase Reference: 4-broMo-5-Methylpicolinaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-broMo-5-Methylpicolinaldehyde(1196157-14-8)
• EPA Substance Registry System: 4-broMo-5-Methylpicolinaldehyde(1196157-14-8)

Safety Data

• Hazardous Substances Data: 1196157-14-8(Hazardous Substances Data)

Usage

Uses

4-?Bromo-?5-?methyl-?2-?pyridinecarbaldehyde is a reagent used in the preparation of voltage-gated sodium channel modulators for therapy.

Upstream product

• 820224-83-7 (4-bromo-5-methylpyridin-2-yl)methanol 
• 17117-24-7 2,5-dimethyl-4-bromopyridine N-oxide 
• 21816-42-2 2,5-dimethyl-4-nitropyridine 1-oxide 
• 4986-05-4 2,5-dimethylpyridine N-oxide 
• 589-93-5 2,5-dimethylpyridine 

Relevant articles and documents

Preparation method of 4 - bromo -2 - (difluoromethyl) -5 - methylpyridine

The invention belongs to the technical field of medical intermediates, and particularly relates to a preparation method of 4 - bromo -2 - (difluoromethyl) -5 - methylpyridine. The compound A is used as a raw material and is sequentially subjected to oxidation reaction, nitration reaction, substitution reaction, reduction reaction, hydrolysis reaction, oxidation reaction and fluoro reaction to prepare 4 - bromo -2 - (difluoromethyl) -5 - methylpyridine, and the prepared 4 -bromo -2 - (difluoromethyl) -5 -5 - 4 -methylpyridine is high in yield and high in purity -2 .