1196709-05-3Relevant academic research and scientific papers
Facile synthesis of 1,4-benzodiazepin-3-ones from o-bromobenzylamines and amino acids via a cascade coupling/condensation process
Wang, Hexiang,Jiang, Yongwen,Gao, Kun,Ma, Dawei
experimental part, p. 8956 - 8960 (2009/12/09)
CuI-catalyzed coupling of 2-bromobenzylamines and α-amino acids and subsequent condensative cyclization (directly or mediated with DPPA) provides 1,4-benzodiazepin-3-ones in moderate yields. Using l-proline and l-valine as the starting materials enantiopu
