119680-08-9

Upstream product

• 6553-96-4 2,4,6-triisopropylphenylsulfonyl chloride 
• 13030-62-1 3',5'-di-O-acetyl-2'-deoxyuridine 

Downstream Products

• 130197-81-8 3',5'-Diacetyl-4-O-(2,4,6-triisopropylphenyl)-2'-deoxyuridine 
• 951-77-9 2'-Deoxycytidine 
• 130197-84-1 3'-O-(2-Cyanoethyl-N,N'-diisopropylphosphoramido)-5'-O-(4,4'-dimethoxytrityl)-4-O-(2,4,6-trimethylphenyl)-2'-deoxyuridine 
• 130197-83-0 5'-(4,4'-Dimethoxytrityl)-4-O-(2,4,6-trimethylphenyl)-2'-deoxyuridine 
• 130197-82-9 4-O-(2,4,6-Trimethylphenyl)-2'-deoxyuridine 
• 951-78-0 2'-deoxyuridine 

Relevant academic research and scientific papers

Identification of single-base mismatches in duplex DNA by EPR spectroscopy

(Figure Presented) The spin-labeled nucleoside TC, containing 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) conjugated to the exocyclic amino group of C, was used to detect single-base mismatches in duplex DNA for the first time by electron paramagnetic re

Nucleic acid intercalating agents

Pyridinone or pyrimidinone nucleoside bases containing fused aromatic polycyclic rings are provided. These polycyclic nucleosides are incorporated into oligonucleotides and hybridized to complementary nucleic acid. Fluorescence spectroscopy and thermal denaturation profiles provided evidence that the polycyclic base is intercalated into the resulting duplex. The fused polycyclic ring systems optionally are substituted with reactive species which inactivate complementary nucleic acids. The oligonucleotides of this invention are useful as improved probes, diagnostic reagents, or for cleaving or derivatizing predetermined domains within nucleic acids.