119690-91-4Relevant academic research and scientific papers
Iridium-Catalyzed Distal Hydroboration of Aliphatic Internal Alkenes
Wang, Guangzhu,Liang, Xinyi,Chen, Lili,Gao, Qian,Wang, Jian-Guo,Zhang, Panke,Peng, Qian,Xu, Senmiao
, p. 8187 - 8191 (2019)
The regioselective hydroboration of aliphatic internal alkenes remains a great challenge. Reported herein is an iridium-catalyzed hydroboration of aliphatic internal alkenes, providing distal-borylated products in good to excellent yields with high regioselectivity (up to 99:1). We also demonstrate that the C?B bond of the distal-borylated product can be readily converted into other functional groups. DFT calculations indicate that the reaction proceeds through an unexpected IrIII/IrV cycle.
Efficient amide-directed catalytic asymmetric hydroboration
Smith, Sean M.,Thacker, Nathan C.,Takacs, James M.
, p. 3734 - 3735 (2008/09/20)
A series of acyclic β,γ-unsaturated amides are shown to undergo highly regio- (>95%) and enantioselective (93-99% ee) rhodium-catalyzed hydroboration with pinacolborane (PinBH) using simple chiral monophosphite or phosphoramidite ligands in combination wi
REACTION OF OXIRANES WITH DIANIONS OF SECONDARY AMINES. NEW ENTRY TO 5-ALKYLSUBSTITUTED γ-LACTAMS
Takahata, Hiroki,Wang, Eng-Chi,Yamazaki, Takao
, p. 1159 - 1166 (2007/10/02)
The oxirane ring cleavage with dilithiated secondary amides was accelerated by the addition of boron trifluoride-etherate to afford γ-hydroxyamides, which were transformed into 5-alkylsubstituted γ-lactams via an intramolecular N-alkylation reaction.
