98857-99-9Relevant academic research and scientific papers
Remarkable levels of enantioswitching in catalytic asymmetric hydroboration
Smith, Sean M.,Takacs, James M.
supporting information; experimental part, p. 4612 - 4615 (2010/12/19)
TADDOL-derived phosphites and phosphoramidites are effective ligands for rhodium-catalyzed asymmetric hydroborations of β,γ-unsaturated amides, achieving up to 99% ee. However, the sense of stereoinduction, R or S, is surprisingly dependent on rather subt
Efficient amide-directed catalytic asymmetric hydroboration
Smith, Sean M.,Thacker, Nathan C.,Takacs, James M.
, p. 3734 - 3735 (2008/09/20)
A series of acyclic β,γ-unsaturated amides are shown to undergo highly regio- (>95%) and enantioselective (93-99% ee) rhodium-catalyzed hydroboration with pinacolborane (PinBH) using simple chiral monophosphite or phosphoramidite ligands in combination wi
