1197010-57-3Relevant articles and documents
Stereoselective total synthesis of a novel regiomer of herbarumin i and its cytotoxic and antimicrobial activities
Jangili, Paramesh,Kashanna, Jajula,Kumar, C. Ganesh,Poornachandra,Das, Biswanath
, p. 325 - 327 (2014)
Stereoselective synthesis of a novel regiomer of the natural nonenolide, herbarumin I has been accomplished. The synthesis involves the coupling of the alcohol and acid fragments of the molecule using Yamaguchi protocol followed by intramolecular ring closing metathesis. The cytotoxic and antimicrobial properties of the synthetic regiomer have been studied.
First asymmetric synthesis of the oxylipin, (6S,9R,10S)-6,9,10- trihydroxyoctadeca-7E-enoic acid
Chatterjee, Sucheta,Kanojia, Seema V.,Chattopadhyay, Subrata,Sharma, Anubha
experimental part, p. 367 - 372 (2011/05/13)
A brief and facile synthesis of the title compound has been developed using cyclohexylideneglyceraldehyde as a chiral template. The key steps in the synthesis were: (i) two highly diastereoselective organometallic addition reactions to the aldehyde to furnish the required synthons with the appropriate stereogenic centers, and (ii) their cross metathesis to give the E-olefin geometry of the target compound.