1197010-57-3

Upstream product

• 164145-69-1 1(S)-[(2R)-1,4-dioxaspiro[4.5]decanyl]-3-buten-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 78008-36-3 (R)-2,3-cyclohexylideneglyceraldehyde 

Downstream Products

• 1197010-63-1 (3S,4R)-3-O-tert-butyl-diphenylsilyl-4,5-O-cyclohexylidene-3,4,5-trihydroxy-pentanal 
• 1312759-13-9 ethyl (6S)-6-tert-butyldiphenylsilyloxyoct-7-enoate 
• 1312759-18-4 ethyl (6S,7E,9R,10S)-6,10-di-tert-butyldiphenylsilyloxy-9-hydroxyoctadecenoate 
• 1312759-08-2 (4S,5R)-4-tert-butyldiphenylsilyloxy-5,6-(cyclohexylidenedioxy)hexan-1-ol 
• 1312759-09-3 (4S,5R)-4-tert-butyldiphenylsilyloxy-5,6-(cyclohexylidenedioxy)hexanal 
• 1312759-10-6 ethyl (2E,6S,7R)-6-tert-butyldiphenylsilyloxy-7,8-(cyclohexylidenedioxy)octenoate 
• 1312759-11-7 ethyl (6S,7R)-6-tert-butyldiphenylsilyloxy-7,8-(cyclohexylidenedioxy)octanoate 
• 1312759-12-8 ethyl (6S,7R)-6-tert-butyldiphenylsilyloxy-7,8-dihydroxyoctanoate 
• 1312759-20-8 C₄₀H₅₀O₉S₂Si 
• 1312413-10-7 (5S,6R)-5-O-tert-butyl-diphenylsilyl-6,7-O-cyclohexylidene-1,5,6,7-tetrahydroxy-hept-2E-ene 
• 1312413-12-9 C₃₀H₄₂O₆SSi 
• 1312413-11-8 (5S,6R)-1-bromo-5-O-tert-butyl-diphenylsilyl-6,7-O-cyclohexylidene-5,6,7-trihydroxy-hept-2E-ene 
• 1312413-13-0 (5S,6R)-3-hydroxymethyl-5-O-tert-butyl-diphenylsilyl-6,7-O-cyclohexylidene-5,6,7-trihydroxy-hept-1-ene 
• 1312413-09-4 (5S,6R)-ethyl-5-O-tert-butyl-diphenylsilyl-6,7-O-cyclohexylidene-5,6,7-trihydroxy-hept-2E-enoate 

Relevant academic research and scientific papers

Stereoselective total synthesis of a novel regiomer of herbarumin i and its cytotoxic and antimicrobial activities

Stereoselective synthesis of a novel regiomer of the natural nonenolide, herbarumin I has been accomplished. The synthesis involves the coupling of the alcohol and acid fragments of the molecule using Yamaguchi protocol followed by intramolecular ring closing metathesis. The cytotoxic and antimicrobial properties of the synthetic regiomer have been studied.

Stereoselective total synthesis of a novel regiomer of herbarumin i and its cytotoxic and antimicrobial activities

Stereoselective synthesis of a novel regiomer of the natural nonenolide, herbarumin I has been accomplished. The synthesis involves the coupling of the alcohol and acid fragments of the molecule using Yamaguchi protocol followed by intramolecular ring closing metathesis. The cytotoxic and antimicrobial properties of the synthetic regiomer have been studied.

First asymmetric synthesis of the oxylipin, (6S,9R,10S)-6,9,10- trihydroxyoctadeca-7E-enoic acid

A brief and facile synthesis of the title compound has been developed using cyclohexylideneglyceraldehyde as a chiral template. The key steps in the synthesis were: (i) two highly diastereoselective organometallic addition reactions to the aldehyde to furnish the required synthons with the appropriate stereogenic centers, and (ii) their cross metathesis to give the E-olefin geometry of the target compound.

A simple entry into 1,3-diols from (R)-2,3-cyclohexylideneglyceraldehyde: synthesis of (-)-galantinic acid

Aldehydes 5, 7, and 9 derived from easily accessible (R)-2,3-cyclohexylideneglyceraldehyde 1 were used as novel substrates to obtain both syn- and anti-1,3-diols in several individual reactions by subjecting each of them to some practically viable metal-m