1312759-08-2

Upstream product

• 1197010-57-3 (2R,3S)-3-tert-butyldiphenylsilyloxy-1,2-(cyclohexylidenedioxy)hex-5-ene 
• 78008-36-3 (R)-2,3-cyclohexylideneglyceraldehyde 
• 164145-69-1 1(S)-[(2R)-1,4-dioxaspiro[4.5]decanyl]-3-buten-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 1312759-13-9 ethyl (6S)-6-tert-butyldiphenylsilyloxyoct-7-enoate 
• 1312759-18-4 ethyl (6S,7E,9R,10S)-6,10-di-tert-butyldiphenylsilyloxy-9-hydroxyoctadecenoate 
• 1312759-09-3 (4S,5R)-4-tert-butyldiphenylsilyloxy-5,6-(cyclohexylidenedioxy)hexanal 
• 1312759-10-6 ethyl (2E,6S,7R)-6-tert-butyldiphenylsilyloxy-7,8-(cyclohexylidenedioxy)octenoate 
• 1312759-11-7 ethyl (6S,7R)-6-tert-butyldiphenylsilyloxy-7,8-(cyclohexylidenedioxy)octanoate 
• 1312759-12-8 ethyl (6S,7R)-6-tert-butyldiphenylsilyloxy-7,8-dihydroxyoctanoate 
• 1312759-20-8 C₄₀H₅₀O₉S₂Si 

Relevant academic research and scientific papers

First asymmetric synthesis of the oxylipin, (6S,9R,10S)-6,9,10- trihydroxyoctadeca-7E-enoic acid

A brief and facile synthesis of the title compound has been developed using cyclohexylideneglyceraldehyde as a chiral template. The key steps in the synthesis were: (i) two highly diastereoselective organometallic addition reactions to the aldehyde to furnish the required synthons with the appropriate stereogenic centers, and (ii) their cross metathesis to give the E-olefin geometry of the target compound.