1312759-10-6Relevant articles and documents
First asymmetric synthesis of the oxylipin, (6S,9R,10S)-6,9,10- trihydroxyoctadeca-7E-enoic acid
Chatterjee, Sucheta,Kanojia, Seema V.,Chattopadhyay, Subrata,Sharma, Anubha
, p. 367 - 372 (2011/05/13)
A brief and facile synthesis of the title compound has been developed using cyclohexylideneglyceraldehyde as a chiral template. The key steps in the synthesis were: (i) two highly diastereoselective organometallic addition reactions to the aldehyde to furnish the required synthons with the appropriate stereogenic centers, and (ii) their cross metathesis to give the E-olefin geometry of the target compound.