1197032-95-3Relevant academic research and scientific papers
5'-SUBSTITUTED BICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM
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, (2011/10/10)
Provided herein are novel 5'-(S)-CH3 substituted bicyclic nucleosides, oligomeric compounds prepared therefrom and methods of using the oligomeric compounds. More particularly, the furanose ring of each of the novel 5'-(S)-CH3 substi
Synthesis and biophysical evaluation of 2′,4′-Constrained 2′O-Methoxyethyl and 2′,4′-Constrained 2′O-Ethyl nucleic acid analogues
Seth, Punit P.,Vasquez, Guillermo,Allerson, Charles A.,Berdeja, Andres,Gaus, Hans,Kinberger, Garth A.,Prakash, Thazha P.,Migawa, Michael T.,Bhat, Balkrishen,Swayze, Eric E.
supporting information; experimental part, p. 1569 - 1581 (2010/06/12)
"Chemical Equation Presented" We have recently shown that combining the structural elements of 2′O-methoxyethyl (MOE) and locked nucleic acid (LNA) nucleosides yielded a series of nucleoside modifications (cMOE, 2′,4′-constrained MOE; cEt, 2′,4′-constrain
