1160288-70-9

Upstream product

• 1093849-11-6 C₃₇H₄₂O₆Si 
• 956485-07-7 ((3aR,6S,6aR)-2,2-dimethyl-6-(naphthalen-2-ylmethoxy)tetrahydrofuro[3,2-d][1,3]dioxole-5,5-diyl)dimethanol 
• 1057385-93-9 (3aR,5S,6R,6aR)-2,2-dimethyl-6-(naphthalen-2-ylmethoxy)tetrahydrofuro[3,2-d][1,3]dioxole-5-carbaldehyde 
• 939-26-4 2-bromomethylnaphthyl bromide 
• 2595-05-3 Diacetone D-glucose 
• 1070968-94-3 C₂₀H₂₄O₆ 
• 956485-08-8 ((3aR,5R,6S,6aR)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyl-6-(naphthalen-2-ylmethoxy)tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanol 
• 620630-82-2 1,2 5,6-O-di(isopropylidene)-α-D-allofuranose 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 1174917-65-7 C₃₈H₄₆O₈SSi 
• 1197032-94-2 (1S,3R,4R,6S,7S)-1-(tert-butyldiphenylsilyloxymethyl)-6-methyl-7-(2-naphthylmethyloxy)-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane 
• 1197032-95-3 (1R,3R,4R,6S,7S)-1-(tert-butyldiphenylsilyloxymethyl)-7-hydroxy-6-methyl-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane 
• 1352230-45-5 C₃₉H₄₄N₂O₇Si 
• 1352230-26-2 C₄₀H₄₆N₂O₉SSi 
• 1352230-33-1 C₄₁H₄₅F₃N₂O₁₁S₂Si 
• 1352231-43-6 C₃₉H₄₃N₃O₅Si 
• 1352230-43-3 C₄₃H₄₈N₂O₉Si 
• 1352230-44-4 C₄₁H₄₈N₂O₁₁S₂Si 
• 1352230-37-5 C₃₉H₄₂N₂O₅SSi 
• 1352230-46-6 C₃₃H₃₄N₂O₇S 
• 1352230-41-1 C₄₂H₅₁N₄O₈PS 
• 1352230-48-8 C₃₉H₄₈N₂O₇SSi 

Relevant academic research and scientific papers

BICYCLIC MORPHOLINO COMPOUNDS AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM

The present invention provides bicyclic morpholino compounds and oligomeric compounds prepared therefrom. More particularly, incorporation of one or more of the bicyclic morpholino compounds into an oligomeric compound is expected to enhance one or more p

Substituted 2′-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom

Provided herein are novel bicyclic nucleosides, oligomeric compounds that include such bicyclic nucleosides and methods of using the oligomeric compounds. More particularly, the novel bicyclic nucleosides comprise a furanose ring system having a bridge co

5'-SUBSTITUTED BICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM

Provided herein are novel 5'-(S)-CH3 substituted bicyclic nucleosides, oligomeric compounds prepared therefrom and methods of using the oligomeric compounds. More particularly, the furanose ring of each of the novel 5'-(S)-CH3 substi

SUBSTITUTED 2 '-AMINO AND 2 '-THIO-BICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM

Provided herein are 2'-amino and 2'-thio bicyclic nucleosides and oligomenc compounds prepared therefrom. The novel bicyclic nucleosides provided herein are expected to be useful for enhancing one or more properties of the oligomeric compounds they are in

Synthesis and biophysical evaluation of 2′,4′-Constrained 2′O-Methoxyethyl and 2′,4′-Constrained 2′O-Ethyl nucleic acid analogues

"Chemical Equation Presented" We have recently shown that combining the structural elements of 2′O-methoxyethyl (MOE) and locked nucleic acid (LNA) nucleosides yielded a series of nucleoside modifications (cMOE, 2′,4′-constrained MOE; cEt, 2′,4′-constrain

6-MODIFIED BICYCLIC NUCLEIC ACID ANALOGS

The present invention provides 6-modified bicyclic nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. In preferred embodiments the nucleoside analogs have either (R) or (S)-chirality at the 6-position. These bicyclicnucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.