119794-93-3Relevant academic research and scientific papers
6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis
-
, (2008/06/13)
Novel position-4 and/or position-6 substituted 5-hydroxy-2,3-dihydrobenzofuran and analogs of the following general structural formula (I) are disclosed: STR1 These compounds are found to be potent inhibitors of leukotriene biosynthesis.
2,3-Dihydro-5-benzofuranols as antioxidant-based inhibitors of leukotriene biosynthesis
Hammond,Kopka,Zambias,Caldwell,Boger,Baker,Bach,Luell,MacIntyre
, p. 1006 - 1020 (2007/10/02)
The enzymes that catalyze the oxidative metabolism of arachidonic acid have provided fertile ground for the development of useful therapeutic agents for nearly a quarter century. Inhibitors of the enzyme cyclooxygenase prevent the formation of the prostag
