1197943-58-0

Basic information

• Product Name: 1-(5-bromo-2-fluorophenyl)butan-1-ol
• Synonyms: 1-(5-bromo-2-fluorophenyl)butan-1-ol
• CAS NO: 1197943-58-0
• Molecular Weight: 247.107
• Mol File: 1197943-58-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(5-bromo-2-fluorophenyl)butan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-bromo-2-fluorophenyl)butan-1-ol(1197943-58-0)
• EPA Substance Registry System: 1-(5-bromo-2-fluorophenyl)butan-1-ol(1197943-58-0)

Safety Data

• Hazardous Substances Data: 1197943-58-0(Hazardous Substances Data)

Upstream product

• 106-94-5 propyl bromide 
• 93777-26-5 5-bromo-2-fluorobenzaldehyde 
• 927-77-5 n-propylmagnesium bromide 

Downstream Products

• 1197943-61-5 1-(5-bromo-2-fluorophenyl)butan-1-one 
• 1197943-62-6 5-bromo-3-propyl-1H-indazole 

Relevant articles and documents

EGFR INHIBITOR, AND PREPARATION AND APPLICATION THEREOF

A 4-substituted-2-(N-(5-substituted allyl amide)phenyl)amino)pyrimidine derivative as represented by formula (I), and a preparation and application thereof as an EGFR inhibitor. The compound has activity of inhibiting the L858R EGFR mutant, the T790M EGFR mutant and the exon 19 deletion activating mutant, may be used to treat diseases mediated alone or in part by EGFR mutant activity, and has a wide application in drugs preventing and treating cancers, particularly non-small cell lung cancer.