119826-71-0Relevant academic research and scientific papers
Large-scale preparation of polyfunctional benzylic zinc reagents by direct insertion of zinc dust into benzylic chlorides in the presence of lithium chloride
Metzger, Albrecht,Argyo, Christian,Knochel, Paul
experimental part, p. 882 - 891 (2010/10/01)
Highly functionalized benzylic zinc chlorides are prepared by the direct insertion of commercially available zinc dust into the corresponding benzylic chlorides in the presence of stoichiometric amount of lithium chloride. These polyfunctional zinc organometallics react with various electrophiles leading to a broad range of functionalized products. Georg Thieme Verlag Stuttgart.
PALLADIUM-CATALYZED CYCLIZATION OF ALKENYL AND ARYL HALIDES CONTAINING α,β-UNSATURATED CARBONYL GROUPS VIA INTRAMOLECULAR CARBOPALLADATION
O'Connor, Brian,Zhang, Yantao,Negishi, Ei-ichi
, p. 3903 - 3906 (2007/10/02)
Treatment of alkenyl and aryl iodides and bromides containing an appropriate α,β-unsaturated carbonyl group with a catalytic amount (3-5 molpercent) of either a Pd(0) or a Pd(II) complex, e.g., Pd(Ph3)4, and a base, e.g., NEt3, can induce highly regiosele
