119869-03-3

Basic information

• Product Name: Acetic acid, (4-chlorophenoxy)-, 2-(aminothioxomethyl)hydrazide
• CAS NO: 119869-03-3
• Molecular Formula: C9H10ClN3O2S
• Molecular Weight: 259.716
• Mol File: 119869-03-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetic acid, (4-chlorophenoxy)-, 2-(aminothioxomethyl)hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, (4-chlorophenoxy)-, 2-(aminothioxomethyl)hydrazide(119869-03-3)
• EPA Substance Registry System: Acetic acid, (4-chlorophenoxy)-, 2-(aminothioxomethyl)hydrazide(119869-03-3)

Safety Data

• Hazardous Substances Data: 119869-03-3(Hazardous Substances Data)

Upstream product

• 106-48-9 4-chloro-phenol 
• 333-20-0 potassium thioacyanate 
• 2381-75-1 (4-chlorophenoxy)acetic acid hydrazide 
• 14426-42-7 ethyl p-chlorophenoxyacetate 
• 122-88-3 4-Chlorophenoxyacetic acid 
• 79-19-6 thiosemicarbazide 

Downstream Products

• 1263183-76-1 C₁₃H₁₀ClN₃O₂S 
• 113056-45-4 5-[(4-Chlorophenoxy) Methyl]-4H-1,2,4-Triazole-3-Thiol 
• 344319-70-6 N-[5-(4-Chloro-phenoxymethyl)-[1,3,4]thiadiazol-2-yl]-2-[(E)-hydroxyimino]-acetamide 
• 84138-73-8 5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-amine 
• 119869-13-5 [5-(4-Chloro-phenoxymethyl)-[1,3,4]thiadiazol-2-yl]-[1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-amine 
• 119869-07-7 [5-(4-Chloro-phenoxymethyl)-[1,3,4]thiadiazol-2-yl]-[1-phenyl-meth-(Z)-ylidene]-amine 

Relevant articles and documents

Synthesis and characterization of biologically important quinoline incorporated triazole derivatives

Triazoles are well recognized in literature for their significant biologically active heterocyclic compounds. Also the quinoline nucleus found in several natural products shows a varied biological activity. Keeping in the view of these observations, a novel series of 6/7/8-substtuted-2-[(5-((4-chlorophenoxy)methyl)-4H-1,2,4-triazol-3-yl)thio]quinoline-3-carbaldehydes and 6/7/8-substituted-2-[(5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio]quinoline-carbaldehydes were synthesized by the condensation of 5-(4-chloro phenoxy methyl)-2,4-dihydro-1,2,4-triazole-3-thiones and 5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiols with 6/7/8-substituted-2-chloro quinoline-3-carbaldehydes. The new series were established by Mass, NMR and IR spectroscopy and were also screened for their antimicrobial activities. A few of the novel compounds exhibited tremendous bioactivities compared to that of normal drug.

THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE

The present invention relates to substituted thiadiazole compounds of the formula (I) and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for modulating SCD activity.