1199807-37-8

Basic information

• Product Name: diethyl 1-(2'-cyanobiphenyl-4-yl)methyl-2-propyl-1H-imidazole-4,5-dicarboxylate
• Synonyms: diethyl 1-(2'-cyanobiphenyl-4-yl)methyl-2-propyl-1H-imidazole-4,5-dicarboxylate
• CAS NO: 1199807-37-8
• Molecular Weight: 445.518
• Mol File: 1199807-37-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl 1-(2'-cyanobiphenyl-4-yl)methyl-2-propyl-1H-imidazole-4,5-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 1-(2'-cyanobiphenyl-4-yl)methyl-2-propyl-1H-imidazole-4,5-dicarboxylate(1199807-37-8)
• EPA Substance Registry System: diethyl 1-(2'-cyanobiphenyl-4-yl)methyl-2-propyl-1H-imidazole-4,5-dicarboxylate(1199807-37-8)

Safety Data

• Hazardous Substances Data: 1199807-37-8(Hazardous Substances Data)

Upstream product

• 114772-54-2 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile 
• 144689-94-1 diethyl 2-(n-propyl)-1H-imidazole-4,5-dicarboxylate 

Downstream Products

• 144690-96-0 1-[{2'-cyanobiphenyl-4-yl}methyl]-4-(1-hydroxy-1-methylethyl)-2-propylimidazol-5-carboxylic acid ethyl ester 

Relevant articles and documents

METHOD FOR PRODUCING 1-BIPHENYLMETHYLIMIDAZOLE COMPOUND

The present invention provides a method for producing a 1-biphenylmethylimidazole compound having superior angiotensin II receptor antagonistic activity, or an intermediate thereof. The present invention provides a method for producing a compound having the formula (5) (R1 , Ra : H, an alkyl group) by oxidizing a compound having the formula (1) (R a : H, an alkyl group) using an oxidizing agent in the presence of a radical initiation reagent, and then reacting with an ammonia-generating reagent and a compound having the formula R 1 CHO (R 1 : H, an alkyl group) or a compound having the formula R1C(ORb)3 (R1: H,an alkyl group; Rb : an alkyl group).