1199828-05-1Relevant articles and documents
Structure based evolution of a novel series of positive modulators of the AMPA receptor
Jamieson, Craig,MacLean, John K.F.,Brown, Christopher I.,Campbell, Robert A.,Gillen, Kevin J.,Gillespie, Jonathan,Kazemier, Bert,Kiczun, Michael,Lamont, Yvonne,Lyons, Amanda J.,Moir, Elizabeth M.,Morrow, John A.,Pantling, John,Rankovic, Zoran,Smith, Lynn
scheme or table, p. 805 - 811 (2011/02/27)
Starting from compound 1, we utilized biostructural data to successfully evolve an existing series into a new chemotype with a promising overall profile, exemplified by 19.
INDANE DERIVATIVES AS AMPA RECEPTOR MODULATORS
-
, (2009/12/28)
The present invention relates to a heterocyclic derivative according to formula (I); wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceut