1200592-28-4Relevant academic research and scientific papers
AlCl3 as an efficient catalyst toward the synthesis of 1,6-dihydropyrazine-2,3-dicarbonitrile derivatives
Bhosale, Shrikar M.,Naik, Nilesh H.,Kusurkar, Radhika S.
, p. 3163 - 3169 (2014/01/06)
Aluminium chloride has been shown to be an efficient catalyst for the multicomponent reactions of diaminomaleonitrile (DAMN), ketones or aldehydes, and isocyanides for the synthesis of 1,6-dihydropyrazine-2,3-dicarbonitrile derivatives using comparative s
Isocyanide-based three-component synthesis of highly substituted 1,6-dihydro-6,6-dimethylpyrazine-2,3-dicarbonitrile, 3,4-dihydrobenzo[g] quinoxalin-2-amine, and 3,4-dihydro-3,3-dimethyl-quinoxalin-2-amine derivatives
Shaabani, Ahmad,Hajishaabanha, Fatemeh,Mofakham, Hamid,Mahyari, Mojtaba,Lali, Bagher
experimental part, p. 246 - 254 (2012/04/10)
A novel and efficient isocyanide-based multicomponent reaction between alkyl or aryl isocyanides 1, 2,3-diaminomaleonitrile (2), naphthalene-2,3- diamines (6) or benzene-1,2-diamine (9), and 3-oxopentanedioic acid (3) or Meldrum's acid (4) or ketones 7 wa
Novel syntheses of tetrahydrobenzodiazepines and dihydropyrazines via isocyanide-based multicomponent reactions of diamines
Shaabani, Ahmad,Maleki, Ali,Hajishaabanha, Fatemeh,Mofakham, Hamid,Seyyedhamzeh, Mozhdeh,Manyari, Mojtaba,Ng, Seik Weng
experimental part, p. 186 - 190 (2010/10/19)
In this work, two novel isocyanide-based mul multicomponent reactions of 1,2-diamine compounds with diketene have been developed as efficient strategies for the synthesis of 2,3,4,5-tetrahydro-lH-benzo[b][l,4]diazepine2-carboxamidcs with regiochemical control and 1,6-dihydropyrazinc-2,3-dicarbonitrilcs in good to excellent yields at ambient temperature.
