1200592-28-4Relevant articles and documents
AlCl3 as an efficient catalyst toward the synthesis of 1,6-dihydropyrazine-2,3-dicarbonitrile derivatives
Bhosale, Shrikar M.,Naik, Nilesh H.,Kusurkar, Radhika S.
, p. 3163 - 3169 (2014/01/06)
Aluminium chloride has been shown to be an efficient catalyst for the multicomponent reactions of diaminomaleonitrile (DAMN), ketones or aldehydes, and isocyanides for the synthesis of 1,6-dihydropyrazine-2,3-dicarbonitrile derivatives using comparative s
Novel syntheses of tetrahydrobenzodiazepines and dihydropyrazines via isocyanide-based multicomponent reactions of diamines
Shaabani, Ahmad,Maleki, Ali,Hajishaabanha, Fatemeh,Mofakham, Hamid,Seyyedhamzeh, Mozhdeh,Manyari, Mojtaba,Ng, Seik Weng
experimental part, p. 186 - 190 (2010/10/19)
In this work, two novel isocyanide-based mul multicomponent reactions of 1,2-diamine compounds with diketene have been developed as efficient strategies for the synthesis of 2,3,4,5-tetrahydro-lH-benzo[b][l,4]diazepine2-carboxamidcs with regiochemical control and 1,6-dihydropyrazinc-2,3-dicarbonitrilcs in good to excellent yields at ambient temperature.
