120095-91-2Relevant academic research and scientific papers
REACTIONS OF THIONYL CHLORIDE WITH C-METHYL HETEROCYCLES. PART 1. THE FORMATION OF DICHLORO(2-QUINOLYL)METHANESULPHENYL CHLORIDES FROM 2-METHYLQUINOLINES
Al-Shaar, Adnan H.M.,Gilmour, David W.,Lythgoe, David J.,McClenaghan, Ian,Ramsden, Christopher A.
, p. 3019 - 3024 (2007/10/02)
Hot thionyl chloride converts 2-methylquinolines (1) into dichloro(2-quinolyl)methanesulphenyl chlorides (2) which upon treatment with secondary amines are transformed into thioamides (7).Reaction of the novel derivatives (2) with amidines gives 5-(2-quinolyl)-1,2,4-thiadiazoles (8) and reaction with anionic nucleophiles results in substitution at sulphur.
