2498-46-6

Usage

Uses

Used in Pharmaceutical Synthesis:
2-Phenylacetimidamide Hydrochloride is used as a key intermediate in the preparation of trifluoromethyl pyrimido[1,3]diazepine compounds. These compounds are of interest in the pharmaceutical industry due to their potential therapeutic properties, including possible applications in the treatment of various diseases and disorders.

InChI:InChI=1/C8H10N2.ClH/c9-8(10)6-7-4-2-1-3-5-7;/h1-5H,6H2,(H3,9,10);1H

Upstream product

• 140-29-4 phenylacetonitrile 
• 5442-34-2 ethyl 2-phenylacetimidate hydrochloride 

Downstream Products

• 96675-97-7 N,N'-Bis-<3-dimethylamino-propyl>-benzamidin 
• 38452-96-9 6-benzyl-2,2,4,4-tetraphenyl-2λ⁵,4λ⁵-[1,5,2,4]diazadiphosphinine 
• 16673-85-1 2-benzyl-6-methyl-4(3H)-pyrimidinone 
• 82551-98-2 5-<(2-hydroxyethyl)thio>-6-methyl-2-(phenylmethyl)-4(1H)-pyrimidinone 
• 509101-36-4 ethyl 2-benzyl-4-methylpyrimidine-5-carboxylate 
• 75276-41-4 4-benzyl-7-methyl-5-propylimidazo<1,5-d>-1,2,4-triazin-1(2H)-one 
• 75276-40-3 N-<1-(3-benzyl-1,6-dihydro-6-oxo-1,2,4-triazin-5-yl)ethyl>butyramide 
• 68282-00-8 2-benzyl-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one 
• 68281-93-6 2-benzyl-7-isobutyl-5-methyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one 
• 68281-83-4 3-benzyl-6-(1-butyrylamino-ethyl)-4H-[1,2,4]triazin-5-one 
• 68281-79-8 N-[1-(3-benzyl-5-oxo-4,5-dihydro-[1,2,4]triazin-6-yl)-ethyl]-3-methyl-butyramide 
• 3740-83-8 2-benzyl-1H-pyrimidine-4,6-dione 
• 7500-45-0 N-benzylphenylacetamide 

Relevant academic research and scientific papers

Two new types of π-conjugation between a fullerene sphere and an addend

Diazirine addition reactions to C60, followed by an HCl elimination step, yielded [6,6] and [5,6] sp2 carbon bridged fullerenes. The [5,6] adducts (alkylidenehomofullerenes) are the first examples of fullerene structures where the ad

Pyrimidine Classical Cannabinoid Compounds and Related Methods of Use

Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.

Pyrimidine Non-Classical Cannabinoid Compounds and Related Methods of Use

Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.

Oxime glucokinase activators

Disclosed herein are pyrazole glucokinase activators of the formula (I): that are useful for the treatment of metabolic diseases and disorders.

REACTIVE INTERMEDIATES IN THE PHOTOLYSIS AND THERMOLYSIS OF 3-CHLORO-3-BENZYLDIAZIRINE

The photochemical and thermal decomposition of 3-chloro-3-benzyldiazirine have been studied in different reaction conditions.The decomposition gives rise to benzylchlorocarbene which can rearrange to E and Z chlorostyrene and/or react with the environment.In the presence of acetic acid the main product is 1-chloro-2-phenylethyl acetate.Experiments with acetic acid-d4 showed that some of the chlorostyrene is formed from the carbocation; other experiments conducted with tetramethylethylene as a carbene trapping agent show that the carbene is formed even in the presence of acetic acid.