1201-86-1

Basic information

• Product Name: (E)-3-(4-FLUORO-PHENYL)-BUT-2-ENOIC ACID
• Synonyms: (E)-3-(4-FLUORO-PHENYL)-BUT-2-ENOIC ACID;(2E)-3-(4-Fluorophenyl)but-2-enoic acid
• CAS NO: 1201-86-1
• Molecular Formula: C₁₀H₉FO₂
• Molecular Weight: 180.1756632
• Mol File: 1201-86-1.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-3-(4-FLUORO-PHENYL)-BUT-2-ENOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(4-FLUORO-PHENYL)-BUT-2-ENOIC ACID(1201-86-1)
• EPA Substance Registry System: (E)-3-(4-FLUORO-PHENYL)-BUT-2-ENOIC ACID(1201-86-1)

Safety Data

• Hazardous Substances Data: 1201-86-1(Hazardous Substances Data)

Usage

General Description

(E)-3-(4-Fluoro-phenyl)-but-2-enoic acid is a chemical compound with the molecular formula C10H9FO2. It is a derivative of butenoic acid, with a fluorine substitution on the phenyl ring. (E)-3-(4-FLUORO-PHENYL)-BUT-2-ENOIC ACID has potential applications in pharmaceuticals, as it may have biological activity and could be used in the development of drugs. Its functional groups make it a versatile building block for the synthesis of other organic compounds. Additionally, the presence of the fluorine atom may confer specific properties or reactivity that could be useful in various chemical processes. Overall, (E)-3-(4-Fluoro-phenyl)-but-2-enoic acid has potential as a valuable intermediate in the chemical and pharmaceutical industries.

Upstream product

• 107-93-7 (E)-but-2-enoic acid 
• 352-34-1 4-fluoro-1-iodobenzene 
• 198889-33-7 methyl (E)-3-(4-fluorophenyl)-3-methylacrylate 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 124-38-9 carbon dioxide 
• 350-40-3 2-(4-fluorophenyl)-1-propene 
• 147471-19-0 (E)-3-(4-fluorophenyl)-2-butenoic acid ethyl ester 
• 115621-54-0 3-(4-fluorophenyl)-2-butenoic acid ethyl ester 

Downstream Products

• 1380394-60-4 (E)-1-(4,4-difluoro-4-(phenylsulfonyl)but-2-en-2-yl)-4-fluorobenzene 

Relevant articles and documents

SELECTIVE ANDROGEN RECEPTOR COVALENT ANTAGONISTS (SARCAS) AND METHODS OF USE THEREOF

This invention relates to selective androgen receptor covalent antagonists, synthetic intermediates and by-products, and related compounds, and compositions comprising the same, and uses thereof in treating androgen receptor dependent diseases and conditions such as hyperproliferations of the prostate including pre-malignancies and benign prostatic hyperplasia, prostate cancer, advanced prostate cancer, castration resistant prostate cancer, triple negative breast cancer, other cancers expressing the androgen receptor, androgenic alopecia or other hyperandrogenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (AR-FL) including pathogenic or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR.

Redox-Neutral Photocatalytic C?H Carboxylation of Arenes and Styrenes with CO2

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Design, synthesis and SARs of novel telomerase inhibitors based on BIBR1532

Telomerase has become one of the new popular targets for the development of anti-tumor drugs. Based on the structural characteristics of the BIBR1532 which has entered the stage of clinical research, six series total of 64 new compounds with diverse struc