120154-96-3Relevant articles and documents
A divergent approach to the total synthesis of the marine pyridoacridine alkaloid eilatin and its synthetic isomer isoeilatin
Plodek, Alois,Bracher, Franz
, p. 1445 - 1447 (2015/03/04)
Herein we report the total synthesis of the heptacyclic pyridoacridine alkaloid eilatin (1) and its synthetic isomer isoeilatin (2). Starting from readily available 9-methyl-3,4-dihydroacridin-1(2H)-one (5) and 2-aminoacetophenone, a divergent synthesis gave alkaloid 1 in seven, and isomer 2 in eight steps.
A two step biomimetic total synthesis of eilatin
Gellerman, Gari,Babad, Malca,Kashman, Yoel
, p. 1827 - 1830 (2007/10/02)
The symmetrical tetraaza heptacyclic alkaloid eilatin (1) was synthesized in a biomimetic two step reaction from catechol and monotrifluoro kynuramine (6) under oxidative conditions in the first step (aq. EtOH, NaIO3) and basic conditions (ammo