148149-00-2

Upstream product

• 61-54-1 tryptamine 
• 1280190-67-1 N-formyl-2-(3-trifluoracetylaminopropionyl)aniline 
• 319-76-6 N-(2-(1H-indol-3-yl)ethyl)-2,2,2-trifluoroacetamide 
• 383-63-1 ethyl trifluoroacetate, 
• 363-36-0 kynuramine 

Downstream Products

• 155107-74-7 6-<2-(3-trifluoroacetamidopropanoyl)anilino>-5,8-quinoline quinone 
• 148149-01-3 4-(2-(3-trifluoroacetylamino)propionylphenylamino)-9-(2-trifluoroacetylamino )ethylacridine-1,2-dione 
• 120154-96-3 dibenzo[b,j]dipyrido[4,3,2-de:2',3',4'-gh][1,10]phenanthroline 
• 114622-04-7 ascididemin 
• 155107-76-9 2,2,2-Trifluoro-N-{3-[2-(4-methoxy-5,8-dioxo-5,8-dihydro-quinolin-6-ylamino)-phenyl]-3-oxo-propyl}-acetamide 

Relevant academic research and scientific papers

A Unified Approach to Polycyclic Alkaloids of the Ingenamine Estate: Total Syntheses of Keramaphidin B, Ingenamine, and Nominal Njaoamine i

Many polycyclic marine alkaloids are thought to derive from partly reduced macrocyclic alkylpyridine derivatives via a transannular Diels-Alder reaction that forms their common etheno-bridged diaza-decaline core ("Baldwin-Whitehead hypothesis"). Rather th

Aggregation-induced emission enhancement of polycyclic aromatic alkaloid derivatives and the crucial role of excited-state proton-transfer

Aggregation-induced emission enhancement (AIEE) phenomenon is observed in the polycyclic aromatic alkaloid derivatives due to the configuration changes in the excited state, which is attributed to intramolecular proton-transfer and the formation of a new

Biomimetic synthesis of ascididemin and derivatives

A two-step biomimetic synthesis of the pentacyclic pyrido[2,3,4- kl]acridine marine alkaloid ascididemin (3a) from quinolinequinone 5a and N- trifluoroacetamidokynuramine (4) is described. The crucial step (6 to 7) involves the simultaneous formation of two pyridine rings in a process which might well offer an explanation for the biogenetic synthesis in marine organisms. The preparation of substituted ascididemins by either starting from substituted quinolinequinones, e.g., 5b to afford 11-methoxyascididemin (3b), or by nitration of 3a to the mono 1- or 3-nitroascididemins (8 and 9 respectively) is reported.