1201566-80-4 Usage
Uses
Used in Organic Synthesis:
Methyl 4,5-dimethoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is used as a reagent in organic synthesis for the formation of carbon-carbon bonds. Its selective reactivity and stability make it a valuable tool in the construction of complex molecular structures.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, Methyl 4,5-dimethoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is used as a building block in the synthesis of various drugs. Its role in creating carbon-carbon bonds is crucial for the development of new medicinal compounds.
Used in Agrochemical Synthesis:
Methyl 4,5-dimethoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is also employed in the synthesis of agrochemicals, contributing to the development of new pesticides and other agricultural products.
Used in Material Science:
In the field of material science, Methyl 4,5-dimethoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is used as a precursor in the preparation of advanced materials with specific properties, such as improved strength or chemical resistance.
Safety Considerations:
It is important to handle Methyl 4,5-dimethoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate with care, as boronic esters can be toxic. Proper safety measures, including the use of a well-ventilated area and appropriate protective equipment, should be taken to minimize health risks during its use in chemical synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 1201566-80-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,1,5,6 and 6 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1201566-80:
(9*1)+(8*2)+(7*0)+(6*1)+(5*5)+(4*6)+(3*6)+(2*8)+(1*0)=114
114 % 10 = 4
So 1201566-80-4 is a valid CAS Registry Number.
1201566-80-4Relevant academic research and scientific papers
Synthesis and biological evaluation of N-substituted benzo[c] phenanthrolines and benzo[c]phenanthrolinones as antiproliferative agents
Genès, Constance,Lenglet, Ga?lle,Depauw, Sabine,Nhili, Raja,Prado, Soizic,David-Cordonnier, Marie-Hélène,Michel, Sylvie,Tillequin, Fran?ois,Porée, Fran?ois-Hugues
scheme or table, p. 2117 - 2131 (2011/06/21)
Benzo[c]phenanthrolines and benzo[c]phenanthrolinones substituted by dialkylaminoalkyl side chains at position N5 and C6, respectively, were synthesised and their biological activity evaluated. They displayed interessant cytotoxicity associated with some DNA interactions. However, the low topoisomerase 1 affinity suggests that other cellular targets are responsible for the antiproliferative activity.
Synthesis of N-substituted benzo[c][1,7]- and benzo[c][1,8] phenanthrolin-(5H)-6-ones through a Pd-mediated Suzuki-Miyaura heteroaryl-aryl coupling reaction
Genès, Constance,Michel, Sylvie,Tillequin, Fran?ois,Porée, Fran?ois-Hugues
experimental part, p. 10009 - 10015 (2010/02/27)
In the course of the search for non-camptothecin topoisomerase I inhibitors we have undertaken the synthesis of N-substituted benzo[c][1,7]- and benzo[c][1,8]phenanthrolinone derivatives. An intermolecular Suzuki-Miyaura heteroaryl-aryl coupling reaction was planned as the key step. Then a nitro reduction followed by a concomitant lactamization achieved the construction of the tetracycle structures. This methodology permitted a rapid and efficient elaboration of biologically potent compounds.
